Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 4 out of 4 results
Recruiting
Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.
Adult, Older Adult
Recruiting
Pennsylvania
Do you have heart failure with reduced ejection fraction and thyroid problems? This study will test whether hormone therapy with liothyronine is safe and effective for treating people who have heart failure with reduced ejection fraction and low triiothyronine (T3) syndrome. Low T3 syndrome is a type of thyroid hormone that helps control many functions of your body. To participate in this study, you must be at least 18 years old and diagnosed with heart failure with reduced ejection fraction. This study is located in Philadelphia, Pennsylvania.
Adult, Older Adult
Recruiting
Pennsylvania
Do you have heart failure with reduced ejection fraction (HFrEF) and an implantable cardioverter defibrillator (ICD)? This study is testing the effectiveness of thyroid hormone therapy with a medicine called liothyronine (LT3) in individuals HFrEF. To participate in this study, you must be at least 18 years old and have Class I, II, or III heart failure. This study takes place in Philadelphia, Pennsylvania.
Adult, Older Adult
Recruiting
Do you have heart failure with preserved ejection fraction (HFPEF)? This study is testing the efficacy of a diuretic medicine called spironolactone that stops your body from absorbing too much salt and keeps your potassium levels from dropping too low. Participants of this study must be between 50 and 99 years old and already taking diuretic medicine. This study takes place in multiple locations across the United States and Sweden.
Adult, Older Adult