Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 7 out of 7 results
Recruiting
Have you had a heart attack, and do you want to help improve strategies for blood transfusion? The study is comparing two strategies for blood transfusions in heart attack patients who have anemia—whether to give a blood transfusion when the hemoglobin level is less than 10 g/dL, or to give blood only when the blood count is below 8 g/dL. To participate in this study, you must be at least 18 years old, have anemia, and be hospitalized for a heart attack. The study is located in New Brunswick, New Jersey.
Adult, Older Adult
Recruiting
Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.
Adult, Older Adult
Recruiting
Massachusetts
Do you have heart failure and feel that your condition is harming your mental and physical well-being? This study is testing the use of an intervention called positive psychology–motivational interviewing (PP-MI). Researchers are exploring whether this 12-week intervention delivered by phone and text message can improve the physical and mental health of people with heart failure. To participate in this study, you must be at least 18 years old. This study takes place in Boston, Massachusetts.
Adult, Older Adult
Recruiting
Does your child have heart disease and require a mechanical circulatory support device such as a ventricular assist device (VAD)? This study is testing the safety and efficacy of a type of VAD called the Jarvik 2015. To participate in this study, your child must weigh between 8 and 30 kilograms (18–66 pounds). This study takes place in multiple locations across the United States.
Child
Recruiting
Massachusetts
Are you a current patient at Massachusetts General Hospital or Brigham and Women’s Hospital with clinical depression and heart failure or unstable chest pain (called angina)? This study is investigating whether 26 weeks of education and increased monitoring from healthcare managers improves psychiatric and heart symptoms better than self-managed care. This study takes place in Boston, Massachusetts.
Adult, Older Adult
Recruiting
Do you have heart failure with preserved ejection fraction (HFPEF)? This study is testing the efficacy of a diuretic medicine called spironolactone that stops your body from absorbing too much salt and keeps your potassium levels from dropping too low. Participants of this study must be between 50 and 99 years old and already taking diuretic medicine. This study takes place in multiple locations across the United States and Sweden.
Adult, Older Adult
Recruiting
Massachusetts
Are you 65 years old or older, and do you have advanced heart failure? This study is comparing how doctors provide their patients with treatment goals. Some participants will watch a video, while others will have a verbal discussion with their healthcare provider. Researchers will then determine which group has more knowledge about their choices and feels more secure about the decisions for their care. To participate in this study, you have to have been hospitalized for heart failure in the past 6 months. This study takes place in Boston, Massachusetts.
Older Adult