Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 10 results
Recruiting
Minnesota
Are you an adult who has had Fontan palliation operation? If so, you may be able to join a clinical trial where researchers learn more about how the heart and lungs work after a Fontan palliation. Researchers will perform a procedure called a cardiac catheterization while participants exercise to see how well the heart is working. Participants must be at least 18 years old. The study is taking place in Rochester, Minnesota.
Adult, Older Adult
Recruiting
Connecticut
Do you have heart failure that is well controlled through medication and attending regular appointments with your healthcare provider? This clinical trial is testing a dietary supplement taken by mouth twice a day for five days to see if it can help patients with heart failure. You must be at least 18 years old to participate. The study is taking place in New Haven, Connecticut.
Adult, Older Adult
Recruiting
Connecticut
Massachusetts
New York
Do you have heart failure? In this clinical trial, researchers are using images of the heart and blood tests to learn more about Black and Hispanic patients with heart failure. You may be able to participate if you are at least 60 years old; of Black, Hispanic, or Caribbean origin; and have been diagnosed with heart failure. The study is taking place in locations in Connecticut, Massachusetts, and New York.
Adult, Older Adult
Recruiting
Minnesota
Are you an adult with mild heart failure and a left bundle branch block? This study will test whether a type of pacemaker called a cardiac resynchronization device can help the heart pump more blood in people who have mild heart failure (HF) and left bundle branch block. In the study, participants will have a cardiac resynchronization device implanted. This study is located in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Do you want to help find new treatments for heart failure with preserved ejection fraction? This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.
Adult, Older Adult
Recruiting
Connecticut
Are you an adult with heart failure and an implanted CardioMEMS pulmonary artery pressure (PAP) monitor? This study is investigating whether psychological stress can make the symptoms of heart failure worse. Participants of this study will have their blood pressure monitored and their blood drawn after undergoing mental stress in a controlled setting, within a laboratory. To participate in this study, you must be at least 18 years old. This study takes place in New Haven, Connecticut.
Adult, Older Adult
Recruiting
Connecticut
Do you have heart failure and need treatment with intravenous (IV) diuretics? This study is exploring the use of chloride supplementation in people with heart failure who require treatment with IV diuretics, which are used to help rid your body of excess water and salt. To participate in this study, you must have heart failure with signs of volume overload (rales, edema, elevated jugular venous pressure [JVP], or weight gain of at least 5 pounds) requiring treatment with IV diuretics. This study takes place in New Haven, Connecticut.
Adult, Older Adult
Recruiting
Minnesota
Are you an adult with mild heart failure (HF) and left bundle branch block (LBBB)? LBBB is a heart condition in which there is a delay or blockage of electrical signals to the left side of the heart. This study is exploring the use of a treatment called cardiac resynchronization therapy (CRT) in people with HF and LBBB. To have CRT, participants must be willing to have an implanted device, called a biventricular pacemaker, that helps the chambers of the heart work together to pump blood more efficiently. To participate in this study, you must be at least 18 years old. This study takes place in Rochester, Minnesota.
Adult, Older Adult
Recruiting
Do you have heart failure with preserved ejection fraction (HFPEF)? This study is testing the efficacy of a diuretic medicine called spironolactone that stops your body from absorbing too much salt and keeps your potassium levels from dropping too low. Participants of this study must be between 50 and 99 years old and already taking diuretic medicine. This study takes place in multiple locations across the United States and Sweden.
Adult, Older Adult
Recruiting
Michigan
Have you experienced a cardiac event in the past 6 months? This study assesses the efficacy of combining center-based and remote- or home-based cardiac rehabilitation sessions. Many patients who require cardiac rehabilitation, including those with angina myocardial infarction, heart failure, heart valve disease, and coronary heart (artery) disease, do not complete the necessary amount of rehabilitation sessions when done in a center-based environment. Researchers are investigating whether a combination approach will help. To participate in this study, you must be between 18 and 85 years old. This study takes place in Detroit, Michigan.
Adult, Older Adult