Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 9 out of 9 results
Recruiting
Maryland
Do you or your child have a lung disease? This study will investigate the genes involved in the breathing process and in the development of lung diseases such as asthma or sarcoidosis to improve understanding of the role they play. To participate in this study, you or your child must be between 2 and 90 years old. This study is located in Bethesda, Maryland, at the NIH Clinical Center.
All Ages
Accepting Healthy Volunteers
Recruiting
Minnesota
Do you have cystic fibrosis and are you eligible for a lung transplant? This study is interested in learning more about the presence and location of certain bacteria in the lungs of people who have cystic fibrosis by examining lungs that have been removed from patients who have cystic fibrosis who are undergoing a lung transplant. To participate in this study, you must be at least 18 years old, have been diagnosed with cystic fibrosis, be eligible for a lung transplant, and have tried all other available treatments without success. This study is located in Minneapolis, Minnesota.
Adult, Older Adult
Recruiting
Florida
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
New York
Do you have overweight? Circadian rhythm disorders can cause overweight and obesity. This study is examining how not getting enough sleep causes these complications. To participate in this study, you must be between the ages of 20 and 40 and have overweight but not obesity. This study is located in New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Minnesota
Are you a healthy adult who regularly sleeps for 6.5 or fewer hours? This study is examining whether getting enough sleep can lower your risk of high blood pressure. To participate in this study, you must be between 18 and 65 years old, regularly sleep for 6.5 or fewer hours, and be able to adjust your sleep schedule for the study. This study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Ohio
Has your newborn been diagnosed with patent ductus arteriosus? Patent ductus arteriosus (PDA) is a condition in which a connection between two major blood vessels close to the heart does not close properly after birth. This affects blood flow to the lungs and may cause neonatal respiratory diseases. PDA may correct itself, but sometimes treatment may be necessary. This study aims to identify ways by which doctors can predict which cases of PDA need to be treated. To participate in this study, your newborn must have been born between 23 and 29 weeks’ gestation and have been diagnosed with PDA. This study is located in Columbus, Ohio.
Child
Recruiting
Indiana
Have you been diagnosed with high blood pressure while pregnant? This study is investigating whether a mother’s blood pressure during pregnancy affects her newborn’s lung development. To participate in this study, your newborn must have been born either prematurely at more than 25 weeks’ gestation or at full term to a healthy mother or a mother who was diagnosed with high blood pressure during pregnancy. This study is located in Indianapolis, Indiana.
All Ages
Recruiting
Florida
Is your newborn in the NICU at Holtz Children’s Hospital in Miami? Newborns born very prematurely often need oxygen therapy or ventilation to help them breathe and survive. This study will help doctors understand how changes in oxygen and carbon dioxide levels while newborns are getting treatment affect how their lungs develop. While your newborn is in the newborn neonatal intensive care unit (NICU), researchers will record his or her oxygen and carbon dioxide levels, heart rate, and other measures. To participate in this study, your newborn must have been born prematurely between 23 and 28 weeks’ gestation, be less than 28 days old, and be receiving oxygen therapy. This study is located in Miami, Florida.
All Ages
Recruiting
Indiana
Was your newborn born prematurely? This study aims to better understand the effects of premature delivery on a baby’s lungs during his or her first year of life. To participate in this study, your newborn must have been born prematurely between 24 and 36 weeks’ gestation and not have any congenital heart or lung defects. This study is located in Indianapolis, Indiana.
Child