Clinical Trials

This study aims to see if a blood test can predict rejection and take the place of biopsies. The test shows how much donor DNA is in a recipient s blood. Adults 18 years and older who are on the lung or heart transplant waitlist are eligible.

The study objective is to compare neurodevelopmental (ND) and behavioral outcomes between children with Down syndrome (DS) who had complete atrioventricular septal defect (CAVSD) repair and children from the same clinical sites with DS without major congenital heart disease (CHD) requiring previous or planned CHD surgery.

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.

Do you have heart disease? This study is looking to improve the quality of heart CT scans by using new methods to create the images. You may be able to participate in the study if you are 18 years old or older, have heart disease, and have been told by your doctor that you need a CT scan. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.

This study is a single center, early phase 1 clinical imaging study designed to assess the dosimetry of 68Ga-Galmydar for PET/CT imaging.

PREVENTABLE is a large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia. It will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.

A single center, phase 0/1 clinical imaging study designed to assess the role of [68Ga]Galmydar PET/CT imaging in human subjects.

This study is intended to evaluate the safety and efficacy of MVT-100 using a single ascending dose design in healthy volunteers.

This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.

Do you have psoriasis? This study is exploring possible links among several diseases associated with chronic inflammation. Participants with an inflammatory disease called psoriasis will be monitored to learn more about whether this condition affects their risk for developing high blood cholesterol, atherosclerosis, and cardiovascular disease, including coronary heart disease. To participate in this study, you must be at least 18 years old and have psoriasis. This study is located in Bethesda, Maryland.