Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 13 results
Recruiting
Illinois
Are you an adult with a diagnosed sleep phase disorder? This study aims to assess the sleep patterns and quality of sleep in people who have sleep phase disorders to determine how the disorders affect their circadian rhythms. To participate in this study, you must be at least 18 years old and have a sleep phase disorder, such as advanced sleep-wake phase syndrome or delayed sleep-wake phase syndrome. This study is located in Chicago, Illinois.
Adult, Older Adult
Recruiting
New York
Do you have overweight? Circadian rhythm disorders can cause overweight and obesity. This study is examining how not getting enough sleep causes these complications. To participate in this study, you must be between the ages of 20 and 40 and have overweight but not obesity. This study is located in New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Minnesota
Are you a healthy adult who regularly sleeps for 6.5 or fewer hours? This study is examining whether getting enough sleep can lower your risk of high blood pressure. To participate in this study, you must be between 18 and 65 years old, regularly sleep for 6.5 or fewer hours, and be able to adjust your sleep schedule for the study. This study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Maryland
Do you or your child have dyslipidemia? This study is exploring how different diagnostic tests can help us understand how lipid disorders, including high blood cholesterol and high blood triglycerides, affect the body. Information from this study may help improve the way lipid disorders are diagnosed or treated in the future. Participants in this study must be at least 2 years old. The study is being conducted in Bethesda, Maryland.
All Ages
Recruiting
Texas
Are you an adult who is healthy or has problems with the level of cholesterol or other lipids in the blood? This study is gathering information on the risk factors for very high or very low levels of lipids, or fats, in the blood. Researchers will collect participants’ demographic information, medical history, and blood samples. To participate in this study, you must be at least 18 years old. This study takes place in Dallas, Texas.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Virginia
Health organizations recommend exercise in an intensity based manner to promote cardiovascular adaptation and prevent disease. Metformin is a common anti-diabetes medication that reduces future type 2 diabetes and cardiovascular disease (CVD) risk. However, the optimal dose of exercise to be combined with metformin for vascular health remains unknown. The purpose of this study is to evaluate whether combining high or low intensity exercise with metformin has the potential to outperform either exercise intensity alone on blood flow across the arterial tree as well as impact insulin action in individuals with metabolic syndrome.
Adult, Older Adult
Recruiting
Virginia
Do you have metabolic syndrome? This trial is testing whether low-intensity exercise or high-intensity exercise works best to lower the risk of heart and blood vessel diseases in people who have metabolic syndrome and are taking a medicine called metformin to treat high blood sugar levels. To participate in this study, you must be between 40 and 80 years old and diagnosed with metabolic syndrome but not type 2 diabetes. This study takes place in New Brunswick, New Jersey.
Adult, Older Adult
Recruiting
South Carolina
Do you or your child have overweight or obesity? This study aims to find effective ways to prevent and treat obesity and metabolic syndrome in African American communities. The study will test the effectiveness of a family-based comprehensive health and fitness programs involving community health workers. Participants must be 12 years old or older and African American and have overweight or obesity. This study takes place in Charleston, South Carolina.
All Ages
Recruiting
Texas
Does your child have higher triglyceride levels but normal cholesterol levels? This study is testing whether a protein supplement called carnitine can help prevent blood vessel stiffness in teenagers who have metabolic syndrome or other risk factors for heart and blood vessel diseases. Participants in this study must be between 13 and 19 years old and have moderate to high blood triglyceride levels but normal blood cholesterol levels. This study takes place in Houston, Texas.
Child, Adult
Recruiting
Massachusetts
Pneumonia is a major public health problem for the elderly and is one of the leading causes of hospitalization and death for this population, particularly for elderly nursing home residents. This planning grants seeks to establish a safe and effective dose of zinc supplementation with the goal to conduct a larger randomized clinical trial to study the effect of zinc supplementation in nursing home elderly with low serum zinc levels on the risk, antibiotic use, and duration of sick days with pneumonia. This project has significant potential to positively impact the health and quality of life in the elderly and to reduce the economic costs associated with their care.
Older Adult
Accepting Healthy Volunteers