Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 11 results
Recruiting
Illinois
Are you an adult with a diagnosed sleep phase disorder? This study aims to assess the sleep patterns and quality of sleep in people who have sleep phase disorders to determine how the disorders affect their circadian rhythms. To participate in this study, you must be at least 18 years old and have a sleep phase disorder, such as advanced sleep-wake phase syndrome or delayed sleep-wake phase syndrome. This study is located in Chicago, Illinois.
Adult, Older Adult
Recruiting
New York
Do you have overweight? Circadian rhythm disorders can cause overweight and obesity. This study is examining how not getting enough sleep causes these complications. To participate in this study, you must be between the ages of 20 and 40 and have overweight but not obesity. This study is located in New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Minnesota
Are you a healthy adult who regularly sleeps for 6.5 or fewer hours? This study is examining whether getting enough sleep can lower your risk of high blood pressure. To participate in this study, you must be between 18 and 65 years old, regularly sleep for 6.5 or fewer hours, and be able to adjust your sleep schedule for the study. This study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
New York
Are you an adult who does not have high blood pressure? Circadian rhythms control daytime and nighttime changes in blood pressure. This study is examining the links between stress, loss of sodium through urine, and circadian rhythms in controlling blood pressure. To participate in this study, you must be at least 21 years old and not have high blood pressure. This study is located in New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Utah
Do you have overweight or obesity and normally sleep between 10 pm and 3 am? This study is investigating how sleep schedules and circadian rhythm misalignment can contribute to increased consumption of energy dense/prepared foods and to decreased insulin sensitivity, which can raise a person's risk of cardiometabolic risk factors. This study is located in Salt Lake City, Utah.
Adult
Accepting Healthy Volunteers
Recruiting
California
Tennessee
Washington
Do you know a newborn or toddler who has severe combined immunodeficiency? This study will test the safety and effectiveness of genetic therapies to treat X-linked severe combined immunodeficiency (SCID-X1), a rare genetic immune disorder. The therapies could be a new approach to treat SCID-X1 in people who do not have a brother or sister to be a donor for stem cell transplant. To participate in this study, the child must be 2 years old or younger. This study is located in Memphis, Tennessee; San Francisco, California; and Seattle, Washington.
Child
Male
Recruiting
Maryland
Are you an adult who has kidney cancer? This study will test how a new genetic therapy approach works for patients who have kidney cancer. A patient’s white blood cells will be modified in the laboratory using genetic therapies. Patients will receive different doses of their own, modified white blood cells. To participate in this study, you must be between 18 and 70 years old and have a diagnosis of progressive renal cell carcinoma. This study is located in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Minnesota
Do you or a child you know have lymphoma? This study is testing a genetic therapy to prevent lymphoma from recurring. Participants in this study must be at least 3 years old and at high risk for recurrent lymphoma as determined by your doctor. This study is located in Chapel Hill, North Carolina.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Maryland
Are you an adult with sickle cell disease or would like to help research? Some people who have sickle cell disease are at greater risk for developing abnormal blood clots (venous thromboembolism). This could be a blood clot in the leg (called deep vein thrombosis) or a clot that can break off and travel to the lung (called a pulmonary embolism). This study will look at the blood of people who have sickle cell disease and venous thromboembolism, as well as healthy volunteers, to help researchers develop better treatments to prevent blood clots. Participants in this study must be between 18 and 80 years old and be either a healthy volunteer or have sickle cell disease or trait. This study is located in Bethesda, Maryland.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Maryland
Are you an adult willing to give blood samples? This study investigates ways to prevent blood clotting in people with sickle cell disease. In this population, blood clotting is the most common cause of vascular death after heart attack and stroke. Scientists are studying the blood of people with sickle cell disease and comparing it with the blood of people without sickle cell disease over 2 years. To participate in this study, you must be between the ages of 18 and 80 years old and willing to participate for up to 2 years. This study takes place in Bethesda, Maryland.
Adult, Older Adult
Accepting Healthy Volunteers