Clinical Trials

Have you been diagnosed with peripartum cardiomyopathy and are within 5 months of your due date? This study is evaluating the effectiveness of a medicine called bromocriptine to treat peripartum cardiomyopathy, or weakness of the heart muscle that occurs during or shortly after pregnancy. To participate in this study, you must be at least 18 years old, diagnosed with peripartum cardiomyopathy, and within 5 months of your delivery date. This study takes place in Pittsburgh, Pennsylvania.

Do you have cardiomyopathy that has led to moderate or severe mitral regurgitation? This study is exploring the best surgical technique to repair mitral regurgitation by comparing two procedures called undersizing mitral annuloplasty (UMA) and papillary muscle approximation (PMA). A UMA is a common procedure that involves implanting a prosthetic ring onto the mitral valve to stop the valve from leaking. A PMA is a newer technique in which a suture draws together the two muscles that connect the mitral valve to the heart muscle prior to performing UMA. To participate in this study, you must be 18 years old or older and have never had a mitral valve repair procedure. This study takes place in Atlanta, Georgia.

The purpose of this study is to see if adding a drug called Regadenoson to the EVLP circulation reservoir during perfusion of marginal donor lungs will help increase the likelihood that the donor lungs will become usable for transplantation.

This project will determine the health impact of parenthood on people with cystic fibrosis (CF). The study team will use retrospective data to provide relatively immediate evidence on parenthood's effect on pulmonary health.

Do you or your child have a lung disease? This study will investigate the genes involved in the breathing process and in the development of lung diseases such as asthma or sarcoidosis to improve understanding of the role they play. To participate in this study, you or your child must be between 2 and 90 years old. This study is located in Bethesda, Maryland, at the NIH Clinical Center.