Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 15 results
Recruiting
Maryland
Do you or your child have a lung disease? This study will investigate the genes involved in the breathing process and in the development of lung diseases such as asthma or sarcoidosis to improve understanding of the role they play. To participate in this study, you or your child must be between 2 and 90 years old. This study is located in Bethesda, Maryland, at the NIH Clinical Center.
All Ages
Accepting Healthy Volunteers
Recruiting
Alabama
Do you have chronic bronchitis and COPD and want to improve treatment? This study will be testing how well a medicine called ivacaftor that is used to treat cystic fibrosis works also to treat symptoms of chronic bronchitis. New research suggests chronic bronchitis may be due to a problem similar to cystic fibrosis. To participate in this study, you must be 40 to 80 years old, have a history of smoking, and have not been diagnosed with asthma or cystic fibrosis. This study will be conducted in Birmingham, Alabama.
Adult, Older Adult
Recruiting
Massachusetts
Do you have COPD? This study will be looking for genes that may play a role in the development of COPD by looking at the blood from patients who have COPD, as well as the blood from those patients’ family members. To participate in this study, you must be 52 years old or younger and must not be pregnant or have other serious lung diseases such as lung cancer. This study will be conducted in Boston, Massachusetts.
All Ages
Recruiting
Maryland
Are you an adult with a lung disease such as COPD, chronic bronchitis, cystic fibrosis, or emphysema? This study aims to discover if low-dose computed tomography (CT) scans are as effective as regular CT scans in monitoring your COPD. This study is located in Bethesda, Maryland, at the NIH Clinical Center.
All Ages
Accepting Healthy Volunteers
Recruiting
New York
Do you have COPD, or are you a healthy volunteer who is willing to do an imaging test? This study will use an imaging test called single-photon emission computed tomography (SPECT) to compare the lung function of patients who have COPD with healthy volunteers who smoke and who do not smoke. The CT scan can detect death of cells in a process called apoptosis, which is linked to severe COPD and cannot be seen in the normal adult lung. To participate in this study, you must be at least 18 years old and either have moderate to severe COPD, not have COPD and be a smoker for longer than 10 years, or not have COPD and never smoked. This study is located in New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
California
Do you have asthma, COPD, or asthma COPD overlap syndrome? This study will look at whether a health coach can help people who have asthma, COPD, or asthma-COPD overlap syndrome with their condition. You will be randomly selected to meet with either a lung specialist alone or a lung specialist and a health coach, who will give you recommendations to improve your care and better manage your condition. To participate in this study, you must be age 18 or older, have asthma or COPD, and not already be seeing a lung specialist. You also must get your care from one of 10 health centers in San Francisco, California. This study is located in San Francisco, California.
Adult, Older Adult
Recruiting
Massachusetts
Are you scheduled for open-heart surgery for your aortic valve? This study aims to look at changes in inflammation and gene activity while surgery patients are on a heart-lung bypass machine. To participate in this study, you must be at least 20 years old and be scheduled for aortic valve surgery, either with or without coronary artery bypass grafting (CABG). This study is located in Boston, Massachusetts.
Adult, Older Adult
Recruiting
Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery? Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
Adult, Older Adult
Recruiting
California
Are you planning to have coronary artery bypass grafting (CABG) surgery to treat your heart disease? This study aims to use computed tomography (CT) imaging to help doctors and their patients make better decisions about heart surgery. To participate in this study, you must be at least 40 years old and be scheduled for a CABG. This study is located in Palo Alto and San Diego, California
Adult, Older Adult
Recruiting
Are you scheduled for a coronary artery bypass grafting (CABG) surgery? This study is looking at whether using two or more arterial grafts instead of one reduces complications following surgery and improves survival rates for patients. To participate in this study, you must be between 18 and 70 years old. This study is in six states and multiple locations around the world.
Adult, Older Adult