Find NHLBI Clinical Trials
Search selected NHLBI-supported ClinicalTrials.gov.and by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at
Showing 1 - 7 out of 7 results
Do you or your child have a lung disease? This study will investigate the genes involved in the breathing process and in the development of lung diseases such as asthma or sarcoidosis to improve understanding of the role they play. To participate in this study, you or your child must be between 2 and 90 years old. This study is located in Bethesda, Maryland, at the NIH Clinical Center.
Do you have chronic bronchitis and COPD and want to improve treatment? This study will be testing how well a medicine called ivacaftor that is used to treat cystic fibrosis works also to treat symptoms of chronic bronchitis. New research suggests chronic bronchitis may be due to a problem similar to cystic fibrosis. To participate in this study, you must be 40 to 80 years old, have a history of smoking, and have not been diagnosed with asthma or cystic fibrosis. This study will be conducted in Birmingham, Alabama.
Do you have COPD? This study will be looking for genes that may play a role in the development of COPD by looking at the blood from patients who have COPD, as well as the blood from those patients’ family members. To participate in this study, you must be 52 years old or younger and must not be pregnant or have other serious lung diseases such as lung cancer. This study will be conducted in Boston, Massachusetts.
Are you an adult with a lung disease such as COPD, chronic bronchitis, cystic fibrosis, or emphysema? This study aims to discover if low-dose computed tomography (CT) scans are as effective as regular CT scans in monitoring your COPD. This study is located in Bethesda, Maryland, at the NIH Clinical Center.
Do you have COPD, or are you a healthy volunteer who is willing to do an imaging test? This study will use an imaging test called single-photon emission computed tomography (SPECT) to compare the lung function of patients who have COPD with healthy volunteers who smoke and who do not smoke. The CT scan can detect death of cells in a process called apoptosis, which is linked to severe COPD and cannot be seen in the normal adult lung. To participate in this study, you must be at least 18 years old and either have moderate to severe COPD, not have COPD and be a smoker for longer than 10 years, or not have COPD and never smoked. This study is located in New York, New York.
Do you have asthma, COPD, or asthma COPD overlap syndrome? This study will look at whether a health coach can help people who have asthma, COPD, or asthma-COPD overlap syndrome with their condition. You will be randomly selected to meet with either a lung specialist alone or a lung specialist and a health coach, who will give you recommendations to improve your care and better manage your condition. To participate in this study, you must be age 18 or older, have asthma or COPD, and not already be seeing a lung specialist. You also must get your care from one of 10 health centers in San Francisco, California. This study is located in San Francisco, California.
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.