Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 51 results
Recruiting
Do you have symptoms of a lung disease (such as long-term wet cough, bronchiectasis, or recurrent pneumonia) with no genetic diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) or primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose and tell the difference between these two conditions. Participants in this study must be 5 to 45 years old and must have symptoms of a serious lung disease but no diagnosis. This study is taking place at multiple locations in the United States and in Canada, including the NIH Clinical Center in Bethesda, Maryland.
Child, Adult
Recruiting
Maryland
Do you have bronchiectasis and get frequent lung infections? This study is exploring what causes frequent lung infections in people with bronchiectasis. Researchers will look at whether changes to a person's genes or immune system can raise the risk of these frequent infections. Participants in this study must be at least 5 years old and either healthy, diagnosed with bronchiectasis, or have a history of frequent lung infections. This study is located at the NIH Clinical Center in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
Maryland
Are you a healthy adult or someone with a history of lung infections such as pneumonia or bronchitis? This study aims to compare fluid and tissue samples from the nose and lungs of healthy adults with people who have a lung disease. Researchers hope to learn why some people are more susceptible to certain infections. This study is located at the NIH Clinical Center in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
North Carolina
Do you or your child have PCD and want to help researchers better understand how cilia are formed? This study aims to identify the genes that control how cilia are formed. Cilia are hairlike structures that line the airways and protects the normal lung. The study will also identify how mutations to these genes can cause PCD. This study takes place in Chapel Hill, North Carolina.
All Ages
Accepting Healthy Volunteers
Recruiting
Missouri
North Carolina
Do you or your child have primary ciliary dyskinesia (PCD) or primary immune deficiency (PID)? This study aims to identify genes that cause these two conditions, which can have similar symptoms. The results from this study will help researchers find new ways to treat breathing and hearing problems caused by these two conditions in a cross-sectional cohort of patients with PCD and PID. Participants in this study must be 5 to 45 years old. This study is taking place at multiple locations in the United States and in Canada.
Child, Adult
Recruiting
Do you or your child have symptoms of a serious lung disease but no diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) and primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose ant tell the difference between these two conditions. Participants in this study must be 5 to 45 years old. This study is taking place at multiple locations in the United States and in Canada.
Child, Adult
Recruiting
Maryland
Are you a former smoker with COPD? Researchers are studying whether taking aspirin can help with COPD symptoms. Participants must be at least 40 years old, be diagnosed with COPD, and have a history of smoking at least 10 packs of cigarettes a year. The study is taking place in Baltimore, Maryland.
Adult, Older Adult
Recruiting
Maryland
Are you an adult diagnosed with COPD? If so, you may be able to participate in a clinical trial where researchers are studying whether a home delivery program with foods meant to help increase the amount of omega-3 that you eat can help with COPD. You must be at least 40 years old and diagnosed with COPD to participate. The study is taking place in Baltimore, Maryland.
Adult, Older Adult
Recruiting
Pennsylvania
Are you a smoker with COPD who is willing to use an e-cigarette to reduce how much you smoke? If so, you may be able to participate in a study that is trying to learn more about the effect of switching from smoking cigarettes to using e-cigarettes on COPD symptoms. You may be able to participate if you are 21 to 74 years old, have mild to moderate COPD, and are willing to try e-cigarettes to cut back on your smoking. The study is taking place in Hershey, Pennsylvania.
Adult, Older Adult