Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

Filter by: Close
Disease or Condition

FILTER BY KEYWORD

Showing 1 - 10 out of 45 results
Recruiting
New Jersey
This study is looking to determine if patients with persistent AF with controlled hypertension or without hypertension who are referred for catheter ablation (PVI) and undergo adjunctive RDN have reduced AF burden at 12 months in comparison to patients who undergo only PVI
Adult, Older Adult
Recruiting
Are you an adult with atrial fibrillation? In this study, researchers are comparing a continuous direct oral anticoagulation (DOAC) use versus time-limited (1 month) DOAC guided by an AF-sensing Smart Watch (AFSW) for persons with atrial fibrillation and a moderate risk of stroke. Participants must be between the ages of 22 and 85 and have a history of atrial fibrillation. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, South Carolina, Texas, Virginia, Wisconsin, and Washington, D.C.
Adult, Older Adult
Recruiting
Massachusetts
Are you at least 18 years old and have scheduled elective valve surgery? You may be able to participate in a study where researchers are investigating whether a type of gene therapy can help prevent a form of atrial fibrillation that occurs after surgery. The study is taking place in Worcester, Massachusetts.
Adult, Older Adult
Recruiting
Minnesota
Are you a Minnesota resident with hypertrophic cardiomyopathy? This study aims to find out how common it is for people with hypertrophic cardiomyopathy to also have sleep apnea. Hypertrophic cardiomyopathy is a disease that causes the heart muscle to thicken. Participants will also wear a heart rhythm monitor to help researchers learn whether sleep apnea is linked to arrhythmia. The study seeks healthy volunteers as well as participants in the Hypertrophic Cardiomyopathy Registry. To participate in this study, you must not have had a catheter ablation procedure to treat atrial fibrillation, had surgery to replace your heart valves, or been treated for sleep apnea. The study is located in Rochester, Minnesota.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Massachusetts
Texas
Do you know someone who will be having heart surgery? This study aims to identify what genetic patterns might cause atrial fibrillation and other adverse events that happen after heart surgery. To participate in this study, you must be between 20 and 90 years old. The study is in three locations in Massachusetts and Texas.
Adult, Older Adult
Recruiting
Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery? Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
Adult, Older Adult
Recruiting
New York
Are you an adult with atrial fibrillation who recently had a catheter ablation procedure? This study will investigate the effectiveness of an implantable cardiac monitor-guided device to monitor participants for recurrent atrial fibrillation following ablation. This study is located in Rochester, New York.
Adult, Older Adult
Recruiting
New York
Are you between the ages of 18 and 50 and diagnosed with Friedreich's ataxia? In this study, researchers are testing a new medication, gene therapy, to treat cardiomyopathy associated with Friedreich's ataxia, and you may be able to participate if you are not taking any corticosteroids or immunosuppressive medications to treat Friedreich's ataxia. This study is taking place in New York City, New York.
Adult
Recruiting
Connecticut
Massachusetts
New York
Do you have heart failure? In this clinical trial, researchers are using images of the heart and blood tests to learn more about Black and Hispanic patients with heart failure. You may be able to participate if you are at least 60 years old; of Black, Hispanic, or Caribbean origin; and have been diagnosed with heart failure. The study is taking place in locations in Connecticut, Massachusetts, and New York.
Adult, Older Adult
Recruiting
California
Are you and adult diagnosed with hypertrophic cardiomyopathy? If so, you may be able to participate in this study where researchers are studying whether exercise helps cardiomyopathy symptoms. You may be able to participate if you are between 18 and 80, have cardiomyopathy, and are able to participate in a 24-week moderate exercise training program. The study is taking place in San Francisco, California.
Adult, Older Adult