Clinical Trials

Do you have psoriasis? This study is exploring possible links among several diseases associated with chronic inflammation. Participants with an inflammatory disease called psoriasis will be monitored to learn more about whether this condition affects their risk for developing high blood cholesterol, atherosclerosis, and cardiovascular disease, including coronary heart disease. To participate in this study, you must be at least 18 years old and have psoriasis. This study is located in Bethesda, Maryland.

Do you or your child have obesity and high blood cholesterol or triglycerides? This study is testing the use of a statin in young people to see whether early treatment of high blood cholesterol can affect the risk of developing plaque in blood vessels. Participants in this study must be age 10-17, have a body mass index (BMI) in the obese range, be fluent in English, and not be pregnant.

Have you had a genetic test that revealed a change (mutation) in the genes that affect your body's elastic fibers? This study aims to learn more about the impact of changes in connective tissue genes on an individual's overall health. To participate in this study, you or your child must be between the ages of 2 and 100 years old. You must have also had a genetic test that identified changes in a gene that affects elastic fibers (e.g., ELN, LOX, MFAP4, FBLN5 and EFEMP). This study is located at the NIH Clinical Center in Bethesda, Maryland.