Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 10 results
Recruiting
Massachusetts
New York
Do you have post-traumatic stress disorder (PTSD) or have experienced a psychosocial trauma, or want to help research? This study uses positron emission tomography/magnetic resonance imaging (PET/MRI) to look at the relationship between psychosocial stress and systemic inflammation/atherosclerosis. This study is located in Boston, Massachusetts, and New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
California
Are you planning to have coronary artery bypass grafting (CABG) surgery to treat your heart disease? This study aims to use computed tomography (CT) imaging to help doctors and their patients make better decisions about heart surgery. To participate in this study, you must be at least 40 years old and be scheduled for a CABG. This study is located in Palo Alto and San Diego, California
Adult, Older Adult
Recruiting
Massachusetts
New York
Do you have post-traumatic stress disorder (PTSD) or have experienced a psychosocial trauma, or want to help research? This study uses positron emission tomography/magnetic resonance imaging (PET/MRI) to look at the relationship between psychosocial stress and systemic inflammation/atherosclerosis. This study is located in Boston, Massachusetts, and New York, New York.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
California
Tennessee
Washington
Do you know a newborn or toddler who has severe combined immunodeficiency? This study will test the safety and effectiveness of genetic therapies to treat X-linked severe combined immunodeficiency (SCID-X1), a rare genetic immune disorder. The therapies could be a new approach to treat SCID-X1 in people who do not have a brother or sister to be a donor for stem cell transplant. To participate in this study, the child must be 2 years old or younger. This study is located in Memphis, Tennessee; San Francisco, California; and Seattle, Washington.
Child
Male
Recruiting
Maryland
Are you an adult who has kidney cancer? This study will test how a new genetic therapy approach works for patients who have kidney cancer. A patient’s white blood cells will be modified in the laboratory using genetic therapies. Patients will receive different doses of their own, modified white blood cells. To participate in this study, you must be between 18 and 70 years old and have a diagnosis of progressive renal cell carcinoma. This study is located in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Minnesota
Do you or a child you know have lymphoma? This study is testing a genetic therapy to prevent lymphoma from recurring. Participants in this study must be at least 3 years old and at high risk for recurrent lymphoma as determined by your doctor. This study is located in Chapel Hill, North Carolina.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Florida
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Florida
Is your newborn in the NICU at Holtz Children’s Hospital in Miami? Newborns born very prematurely often need oxygen therapy or ventilation to help them breathe and survive. This study will help doctors understand how changes in oxygen and carbon dioxide levels while newborns are getting treatment affect how their lungs develop. While your newborn is in the newborn neonatal intensive care unit (NICU), researchers will record his or her oxygen and carbon dioxide levels, heart rate, and other measures. To participate in this study, your newborn must have been born prematurely between 23 and 28 weeks’ gestation, be less than 28 days old, and be receiving oxygen therapy. This study is located in Miami, Florida.
All Ages
Recruiting
Minnesota
Are you or a loved one on a ventilator in the hospital in Minnesota? This study is finding out whether people who are on a ventilator sleep better and have less anxiety if they can control their own sedation medicine. To participate in this study, you must be at least 18 years old and receiving mechanical ventilation while hospitalized. This study is located in Minneapolis and Rochester, Minnesota.
Adult, Older Adult
Recruiting
California
Is your child on a ventilator at Children’s Hospital Los Angeles? Ventilators can sometimes weaken the muscles around the lungs, especially in children. This study is testing whether a new computer method to control ventilators can help prevent muscle weakness in children. To participate in this study, your child must be between 1 month and 18 years old and have been on a ventilator for less than 48 hours (or 72 if they were transferred from another hospital) because of a serious lung disease. This study is located in Los Angeles, California.
Child, Adult