Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 11 - 20 out of 43 results
Recruiting
California
Are you an adult who has asthma, or are you willing to be a healthy volunteer? This study is looking at the DNA in airway cells to see how they differ between people who have asthma and people who do not. To get a sample of cells from your airways, you may have a bronchoscopy (a tube inserted through your mouth into your airways). To participate in this study, you must be between 18 and 70 years old, either with asthma or with no history of asthma. This study is located in San Francisco, California.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Colorado
Do you have asthma and obesity and live near Aurora, Colorado? Obesity can lead to widespread inflammation that may make asthma worse. This study will test whether a medicine called CXA-10 reduces inflammation in the airways and body and improves asthma symptoms in people who have obesity. To participate in this study, you must be between 18 and 65 years old, have a BMI of 30 or greater, and have been on long-acting controller medicine—such as inhaled corticosteroids or long-acting beta2-agonists—for at least three months. This study is located in Aurora, Colorado.
Adult, Older Adult
Recruiting
North Carolina
Are you an adult with both asthma and obesity? This study is testing whether a medicine called L-citrulline can help treat asthma and improve lung function in people who have obesity. To participate in this study, you must be 18 to 65 years old and have asthma and obesity. This study takes place in Durham, North Carolina.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Wisconsin
Has your child been treated for an asthma attack with an oral corticosteroid medicine in the last 12 months? A study team will recruit 60 teens and young adults (between 12 and 21 years old) with persistent asthma who are at high risk for future exacerbation. This study examines the contribution of interleukin 1 beta (IL-1β), a protein that is involved in the inflammatory response, in asthma flare-ups. This study takes place in Chapel Hill, North Carolina.
Adult
Recruiting
Georgia
Are you a woman with coronary microvascular dysfunction? In this clinical trial, researchers are studying coronary microvascular dysfunction, which occurs when there are problems in the small blood vessels in the heart. It frequently causes chest pain and is more common in women. The researchers want to learn how daily life and mental stress affect the heart. You may be able to participate if you are at least 45 years old, have gone through menopause, and are willing to undergo tests to measure your stress level. The study is taking place at locations in Atlanta, Georgia.
Adult, Older Adult
Female
Recruiting
North Carolina
Are you an adult who gets little exercise and sits a lot every day? If you sit for more than 8 hours a day and exercise less than 90 minutes per week, this study may interest you. Researchers want to see if walking or standing breaks during long sitting periods can make your heart healthier. To take part in this study, you must be 36 to 55 years old. You also should be able to walk four blocks and go up two flights of stairs. The study is taking place in Chapel Hill, North Carolina.
Adult
Accepting Healthy Volunteers
Recruiting
California
Illinois
New York
Is your family from India, Pakistan, Bangladesh, Nepal, or Sri Lanka? If so, you may be able to participate in a clinical study looking at cardiovascular disease, such as heart disease and stroke among people of South Asian descent. Participants must be between 40 and 84 years old and have no history of heart attack or stroke, heart failure, angina, or atrial fibrillation. This study is taking place in San Francisco, California, Chicago, Illinois, and New York City, New York.
Adult, Older Adult
Not yet recruiting
Georgia
Maryland
Do you have heart disease? This study is looking to improve the quality of heart CT scans by using new methods to create the images. You may be able to participate in the study if you are 18 years old or older, have heart disease, and have been told by your doctor that you need a CT scan. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Alabama
Have you lived in Alabama, Kentucky, Louisiana, or Mississippi for at least two years and are you interested in participating in a clinical study where researchers are trying to better understand health and disease in rural areas? The study team will track your physical activity using a provided Fitbit device and will also ask questions about your health and lifestyle through a cell phone app. You will also receive a kit to measure environmental and health factors in your homes. Participants must live in one of these counties: Dallas County, Alabama; Wilcox County, Alabama; Boyle County, Kentucky; Perry County, Kentucky; Garrard County, Kentucky; Breathitt County, Kentucky; Assumption Parish, Louisiana; Franklin Parish, Louisiana; Oktibbeha County, Mississippi; and Panola County, Mississippi.
Adult
Accepting Healthy Volunteers
Recruiting
Minnesota
Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. In this clinical trial, researchers are studying the link between hot flashes and cardiovascular disease in women. Participants must be between 40 and 60 years old and must not have cardiovascular disease. The study is taking place in Rochester, Minnesota.
Adult
Accepting Healthy Volunteers
Female