Find NHLBI Clinical Trials and Studies

Search selected NHLBI-supported  clinical trials  and  observational studies  by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 9 out of 9 results
Recruiting
California
This study is testing whether a medicine called metformin can help treat aortic aneurisms in the abdomen. The study will use imaging tests to examine whether metformin can help prevent these aortic aneurisms from getting bigger. To participate in this study, you must be 55 to 90 years old and diagnosed with an abdominal aortic aneurism. This study takes place in Stanford, California.
Adult, Older Adult
Recruiting
North Carolina
Would you like more support with your heart and metabolic health? Would you like more support with your heart and metabolic health? This study will provide patients with personalized information about community-based resources to support health-related social needs and heart and metabolic health. You may be able to participate if you are 2 years or older, African American or Black, and you have at least one cardiometabolic condition. Conditions may include being overweight, having high blood pressure, pre-diabetes or diabetes, and/or high cholesterol. This study is recruiting in Rocky Mount, North Carolina.
All Ages
Recruiting
Maryland
Do you or your child have dyslipidemia? This study is exploring how different diagnostic tests can help us understand how lipid disorders, including high blood cholesterol and high blood triglycerides, affect the body. Information from this study may help improve the way lipid disorders are diagnosed or treated in the future. Participants in this study must be at least 2 years old. The study is being conducted in Bethesda, Maryland.
All Ages
Recruiting
Texas
Are you an adult who is healthy or has problems with the level of cholesterol or other lipids in the blood? This study is gathering information on the risk factors for very high or very low levels of lipids, or fats, in the blood. Researchers will collect participants’ demographic information, medical history, and blood samples. To participate in this study, you must be at least 18 years old. This study takes place in Dallas, Texas.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Wisconsin
Do you have a high-risk pregnancy? This study will investigate the use of a non-invasive scan called fetal magnetocardiography to detect potential problems in the fetus in five high-risk pregnancy conditions associated with stillbirth. The scan is normally used to look at fetal heart rhythms. To participate in this study, you must be at least 18 years old and pregnant with one of the following: having a stillbirth in a previous pregnancy, carrying identical twins, or having a fetus that has been diagnosed with major congenital heart disease, fetal hydrops, or fetal gastroschisis. This study takes place in Madison and Milwaukee, Wisconsin.
Adult, Older Adult
Female
Recruiting
Indiana
Are you a woman who is postmenopausal or a man older than 65? This study will investigate the effects of oral progesterone for older women and testosterone for older men on QT intervals. QT intervals that are increased by medicine can lead to dangerous heart rhythm problems. Researchers hope to learn more about why this happens and how to deliver safer doses. This study is located in Indianapolis, Indiana.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Do you or a loved one have pneumonia? This study will test whether combining two medicines to reduce inflammation of the airway and to keep it open may help prevent respiratory failure in people who have pneumonia. To participate in this study, you must be at least 18 years old and have severe pneumonia with low blood oxygen levels.
Adult, Older Adult
Recruiting
Do you have symptoms of a lung disease (such as long-term wet cough, bronchiectasis, or recurrent pneumonia) with no genetic diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) or primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose and tell the difference between these two conditions. Participants in this study must be 5 to 45 years old and must have symptoms of a serious lung disease but no diagnosis. This study is taking place at multiple locations in the United States and in Canada, including the NIH Clinical Center in Bethesda, Maryland.
Child, Adult
Recruiting
Maryland
Are you a healthy adult or someone with a history of lung infections such as pneumonia or bronchitis? This study aims to compare fluid and tissue samples from the nose and lungs of healthy adults with people who have a lung disease. Researchers hope to learn why some people are more susceptible to certain infections. This study is located at the NIH Clinical Center in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers