Clinical Trials and Studies

Do you have cholesterol deposits in your heart arteries and you don’t take medicine to lower your cholesterol? This study is educating people with cholesterol deposits in their heart about the importance of taking medicines to lower cholesterol to prevent heart attacks and other heart diseases. To participate in this study, you should be 18 to 75 years old and have heart disease. This study is in Durham, North Carolina.

Are you a former smoker with COPD? Researchers are studying whether taking aspirin can help with COPD symptoms. Participants must be at least 40 years old, be diagnosed with COPD, and have a history of smoking at least 10 packs of cigarettes a year. The study is taking place in Baltimore, Maryland.

Are you an adult diagnosed with COPD? If so, you may be able to participate in a clinical trial where researchers are studying whether a home delivery program with foods meant to help increase the amount of omega-3 that you eat can help with COPD. You must be at least 40 years old and diagnosed with COPD to participate. The study is taking place in Baltimore, Maryland.

Are you a smoker with COPD who is willing to use an e-cigarette to reduce how much you smoke? If so, you may be able to participate in a study that is trying to learn more about the effect of switching from smoking cigarettes to using e-cigarettes on COPD symptoms. You may be able to participate if you are 21 to 74 years old, have mild to moderate COPD, and are willing to try e-cigarettes to cut back on your smoking. The study is taking place in Hershey, Pennsylvania.

Have you received treatment from a doctor for COPD that has gotten worse and have you been referred for pulmonary rehabilitation, which can help ease the symptoms of COPD.? In this study, researchers are comparing two ways to encourage people to participate in pulmonary rehabilitation. Participants must be at least 40 years old and be willing to participate in calls with a peer coach and view videos. The study is taking place in Springfield, Massachusetts.

Do you have COPD? Researchers in this study are studying the benefit of a wellness program for people with COPD. You may be able to participate if you are at least 40 years old, diagnosed with COPD, and able to perform exercises with your lower body. The study is taking place in San Francisco, California.

Are you a current or former smoker? This study will evaluate if treatment with blood thinners (aspirin and clopidogrel) improves blood flow in the lungs Each participant will take the medicine or placebo, each for 2 weeks, in a random order over 6 weeks and will be evaluated by a computer tomography of the chest two times during the study period. To participate in this study, you should be 50 to 75 years old, current or former smoker and either have COPD or normal lung function. This study is recruiting in Boston, Massachusetts.

Do you have asthma or chronic obstructive pulmonary disease (COPD)? This study will evaluate if the medicine N-Acetylcysteine (NAC) aerosol delivered with positive pressure reduces mucus in the lungs and enhances lung function compared to NAC delivered without positive pressure. To participate in this study, you should be 18 to 85 years old, have asthma or COPD, and be able to take lung function tests. This study is recruiting in San Francisco, California.

Are you a former smoker and do you have chronic obstructive pulmonary disease (COPD)? This study is testing if cleaning the air in your house with an air filter will improve your quality of life by reducing your COPD symptoms and having to take less medicines. To participate in this study, you should be 40 years old or older, have COPD, and have smoked for at least 6 months. This study has multiple locations.

Do you or your child have a lung disease? This study will investigate the genes involved in the breathing process and in the development of lung diseases such as asthma or sarcoidosis to improve understanding of the role they play. To participate in this study, you or your child must be between 2 and 90 years old. This study is located in Bethesda, Maryland, at the NIH Clinical Center.