Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 13 results
Recruiting
Georgia
Did you recently give birth to a very low birth weight infant? The study is investigating how anemia and red blood cell transfusions affect oxygen levels in the digestive tract of very low birth weight infants. To participate in this study, your newborn must have had a very low birth weight and be within seven days of birth. The study is taking place in Atlanta, Georgia.
Child
Recruiting
Maryland
Minnesota
Are you considering a blood stem cell transplant? This study is investigating a new method for collecting blood stem cells from donors to see if it reduces transplant complications, such as rejection, in patients who have blood diseases. To participate in this study, you must have a well-matched donor; you and your donor must be between 4 and 80 years old; and you must not be a candidate for immunosuppressive therapy. This study is located in Bethesda, Maryland.
All Ages
Recruiting
New York
Do you or a family member have Diamond-Blackfan anemia? This registry seeks to collect information from patients who have Diamond-Blackfan anemia (DBA), in order to help researchers and doctors learn more about the condition. The registry will also help connect patients with DBA to research and clinical studies, and possible treatment options. The registry accepts all patients diagnosed with DBA.
All Ages
Recruiting
Maryland
Do you have short telomeres and a telomere gene mutation? Some people who have aplastic anemia have very short telomeres, which protect the ends of DNA in chromosomes. This study is testing whether low doses of the medicine danazol help prevent telomeres from getting shorter and reduce signs of damage from aplastic anemia or related conditions. Participants in this study must be 3 years or older and have a telomere disease and signs of aplastic anemia, lung disease such as pulmonary fibrosis, or liver disease. This study is located in Bethesda, Maryland.
All Ages
Recruiting
Maryland
Have you received a stem cell transplant? This study aims to monitor the long-term health of patients who have received a donor stem cell transplant from the NIH Clinical Center. To participate in this study, you must be between 10 and 80 years old and had your transplant more than 3 years ago. This study is located in Bethesda, Maryland.
All Ages
Accepting Healthy Volunteers
Recruiting
Are you scheduled for a stem cell transplant with cord blood? This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
All Ages
Recruiting
Georgia
Would you like to donate blood for a study of stored red blood cells? This study is evaluating how blood donors affect the stability of stored red blood cells. After collecting a blood sample from a healthy donor, researchers treat the red blood cells with a B vitamin called biotin and then store the sample. After about 1 week, some of the cells are transfused back into the donor to check how many of the red blood cells are still healthy after storage. After a few more weeks, more of the stored cells are transfused and tested again. To participate, your blood must meet certain requirements and you must be healthy, 18 years old or older, and weigh at least 110 pounds. This study is located in Pittsburgh, Pennsylvania.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Minnesota
Are you or a loved one on a ventilator in the hospital in Minnesota? This study is finding out whether people who are on a ventilator sleep better and have less anxiety if they can control their own sedation medicine. To participate in this study, you must be at least 18 years old and receiving mechanical ventilation while hospitalized. This study is located in Minneapolis and Rochester, Minnesota.
Adult, Older Adult
Recruiting
California
Is your child on a ventilator at Children’s Hospital Los Angeles? Ventilators can sometimes weaken the muscles around the lungs, especially in children. This study is testing whether a new computer method to control ventilators can help prevent muscle weakness in children. To participate in this study, your child must be between 1 month and 18 years old and have been on a ventilator for less than 48 hours (or 72 if they were transferred from another hospital) because of a serious lung disease. This study is located in Los Angeles, California.
Child, Adult
Recruiting
Maryland
Are you being treated in the ICU for acute respiratory failure? This study is looking at whether treating depression along with physical therapy helps people recover faster from respiratory failure. After leaving the ICU, you will be visited at your home by a physical therapist and occupational therapist who will talk to you about your goals for recovery and what activities you value the most. They will then design a plan for you that includes a type of talk therapy for depression called behavioral activation. To participate in this study, you must be at least 18 years old and undergoing treatment for acute respiratory failure for more than 24 hours in the ICU. This study is located in Baltimore, Maryland.
Adult, Older Adult