Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 3 out of 3 results
Recruiting
This is a phase 3 study designed to evaluate whether the administration of ganciclovir increases ventilator-free days in immunocompetent patients with sepsis associated acute respiratory failure. Our hypothesis is that IV ganciclovir administered early in critical illness will effectively suppress CMV reactivation in CMV seropositive adults with sepsis-associated acute respiratory failure thereby leading to improved clinical outcomes.
Adult, Older Adult
Recruiting
This study is a multi-center, randomized, partially double-blind, and placebo-controlled Phase Ib clinical trial of inhaled CO (iCO) for the treatment of sepsis-induced acute respiratory distress syndrome (ARDS). The purpose of this study is to evaluate the safety and accuracy of a Coburn-Forster-Kane (CFK) equation-based personalized iCO dosing algorithm to achieve a target carboxyhemoglobin (COHb) level of 6-8% in patients with sepsis-induced ARDS.
Adult, Older Adult
Recruiting
Maryland
Are you recovering after treatment for ARDS? This study aims to test a rehabilitation intervention with patients who are recovering from ARDS and have symptoms of depression. The intervention includes periodic visits from physical and occupational therapists, an exercise regimen, and regular check-ins by phone. To participate in this study, you must be at least 18 years old and recovering at home after hospital treatment for ARDS or another type of acute respiratory failure. This study is located in Baltimore, Maryland.
Adult, Older Adult