Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

Filter by: Close
Disease or Condition

FILTER BY KEYWORD

Showing 1 - 9 out of 9 results
Recruiting
Florida
Are you an adult who does not have high blood pressure and is interested in research? This study will investigate how the brain regulates the body’s response to stress and how infection with HIV or pre-hypertension affects regulation. Your heart and brain activity will be measured while you are at rest, during a mentally stressful task, and while you feel angry. The study will also test whether a breathing exercise improves regulation. People with and without HIV and pre-hypertension will be included. To participate in this study, you must be between 21 and 65 years old and not have high blood pressure. This study is located in Miami, Florida.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Wisconsin
Do you have a high-risk pregnancy? This study will investigate the use of a non-invasive scan called fetal magnetocardiography to detect potential problems in the fetus in five high-risk pregnancy conditions associated with stillbirth. The scan is normally used to look at fetal heart rhythms. To participate in this study, you must be at least 18 years old and pregnant with one of the following: having a stillbirth in a previous pregnancy, carrying identical twins, or having a fetus that has been diagnosed with major congenital heart disease, fetal hydrops, or fetal gastroschisis. This study takes place in Madison and Milwaukee, Wisconsin.
Adult, Older Adult
Female
Recruiting
Indiana
Are you a woman who is postmenopausal or a man older than 65? This study will investigate the effects of oral progesterone for older women and testosterone for older men on QT intervals. QT intervals that are increased by medicine can lead to dangerous heart rhythm problems. Researchers hope to learn more about why this happens and how to deliver safer doses. This study is located in Indianapolis, Indiana.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Michigan
The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.
Adult, Older Adult
Recruiting
Illinois
The purpose of this study is to develop and optimize a targeted behavioral intervention for sleep disturbance among individuals who have recently lost a spouse/long-term cohabitating partner.
Adult, Older Adult
Accepting Healthy Volunteers
Recruiting
Illinois
Are you an adult with a diagnosed sleep phase disorder? This study aims to assess the sleep patterns and quality of sleep in people who have sleep phase disorders to determine how the disorders affect their circadian rhythms. To participate in this study, you must be at least 18 years old and have a sleep phase disorder, such as advanced sleep-wake phase syndrome or delayed sleep-wake phase syndrome. This study is located in Chicago, Illinois.
Adult, Older Adult
Recruiting
Maryland
Do you get less than 7 hours of sleep each day and take medicine for opioid use disorder (OUD)? This study is looking at how the brain systems that control sleep can affect medication-assisted treatment in people who have opioid use disorder. The study will test whether suvorexant can help improve sleep and reduce stress without interfering with treatments for OUD. To participate in this study, you must be 21 to 65 years old. This study takes place at various locations in Baltimore, Bel Air, and Elkton, Maryland.
Adult, Older Adult
Recruiting
Michigan
Do you have mild sleep apnea, or do you just want to help research? This study aims to understand how mild sleep apnea and not getting enough sleep contribute to daytime sleepiness. The study will also test which of three different treatment programs is most effective at preventing daytime sleepiness. To participate in this study, you must be at least 18 years old. This study takes place in Detroit, Michigan.
Adult, Older Adult
Accepting Healthy Volunteers