Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.

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Showing 1 - 10 out of 12 results
Recruiting
Have you had a heart attack, and do you want to help improve strategies for blood transfusion? The study is comparing two strategies for blood transfusions in heart attack patients who have anemia—whether to give a blood transfusion when the hemoglobin level is less than 10 g/dL, or to give blood only when the blood count is below 8 g/dL. To participate in this study, you must be at least 18 years old, have anemia, and be hospitalized for a heart attack. The study is located in New Brunswick, New Jersey.
Adult, Older Adult
Recruiting
Are you scheduled for a stem cell transplant with cord blood? This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
All Ages
Recruiting
Are you an adult woman who would like to help develop methods to prevent the worsening of LAM? This study aims to discover whether earlier and longer treatment with a lower dose of sirolimus can help prevent LAM from getting worse over time. To participate in this study, you must be female, be at least 18 years old, and have been diagnosed with LAM. This study is located in Atlanta, Georgia; Boston, Massachusetts; Chicago, Illinois; Cincinnati, Ohio; Denver, Colorado; Nashville, Tennessee; Palo Alto, California; Philadelphia, Pennsylvania; and Seattle, Washington.
Adult, Older Adult
Female
Recruiting
Are you an adult with B-cell blood cancer who has had at least two treatments fail? This study investigates a new drug (NX-2127) that may be used to treat certain B-cell blood cancers including leukemia and lymphoma. NX-2127 is taken by mouth and works by blocking a specific protein in cancer tumor cells called Bruton's tyrosine kinase (BTK). This study is located at the NIH Clinical Center in Bethesda, Maryland.
Adult, Older Adult
Recruiting
Do you have symptoms of a lung disease (such as long-term wet cough, bronchiectasis, or recurrent pneumonia) with no genetic diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) or primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose and tell the difference between these two conditions. Participants in this study must be 5 to 45 years old and must have symptoms of a serious lung disease but no diagnosis. This study is taking place at multiple locations in the United States and in Canada, including the NIH Clinical Center in Bethesda, Maryland.
Child, Adult
Recruiting
Washington
Are you an adult with pulmonary arterial hypertension (PAH) and currently taking vasodilators? This study is testing the efficacy of a new medicine called famotidine for people with PAH. Participants in this study must be between 18 and 80 years old and willing to take famotidine or a placebo for 6 months. This study takes place in Seattle, Washington.
Adult, Older Adult
Recruiting
Are you or your child between 12 and 35 years old, currently using an inhaler to treat asthma, and interested in supporting research into telehealth to control and improve asthma symptoms? This study is evaluating the use of video telehealthcare to help adolescents and young adults with asthma take their medication correctly and on time. This study takes place in multiple locations across the United States.
Child, Adult
Recruiting
Washington
Are you an adult diagnosed with cystic fibrosis who would like to help test web-based educational resources designed to inform and prepare patients to make decisions about lung transplantation? This study will determine if it is feasible for study participants to complete use of an assigned web-based educational program, and evaluate whether providing certain educational resources leaves participants more prepared to make future treatment decisions involving lung transplantation with their health care provider(s). To participate in this study, you must be at least 18 years old. This study takes place in Seattle, Washington.
Adult, Older Adult
Recruiting
Are you an adult who has been diagnosed with idiopathic pulmonary fibrosis (IPF)? This study will examine whether adding N-acetylcysteine (NAC) to standard treatment improves key indicators of IPF, including symptoms, in people with the TOLLIP rs3750920 TT genotype who are living with the disease. You must be age 40 or older to participate in this study. This study takes place in multiple locations.
Adult, Older Adult