Clinical Trials

The main goal of this study is to determine whether the treatment will lead to a complete absence of severe vaso-occlusive events (VOEs) in patients with severe SCD.

Do you or your child have sickle cell disease and also have an interest in contributing to long-term data collection? This study is monitoring patients and collecting biological samples from patients who have sickle cell disease to better understand long-term outcomes. Participants can be any age and must have sickle cell disease. This study is located in six sites in Illinois, Louisiana, North Carolina, and Tennessee.

Do you or your child have sickle cell disease and access to a smart phone? This study tests whether a mobile app can help adolescents and young adults who have sickle cell disease take medicine, such as hydroxyurea, correctly and on time. To participate in this study, you or your child must be between 12 and 21 years old, have sickle cell disease, and be currently taking hydroxyurea. This study takes place in Chicago, Illinois.

Do you or your child have sickle cell disease? This study aims to develop a mathematical equation to estimate the functioning of the kidneys in children and adults with sickle cell disease. To participate in this study, you or your child must be between 5 and 50 years old. This study takes place in Birmingham, Alabama; Chicago, Illinois; and Memphis, Tennessee.