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The DNA Sequencing and Computational Biology Core (DSGC) was established in 2010 to meet the increasing demands of NHLBI investigators for next-generation sequencing. The main goal of the DSGC is to foster large-scale genomics research at DIR by providing access to cutting-edge sequencing instrumentation and genome technology. As an integral part of the research community at NHLBI, the DSGC provides standard and advanced services for experimental consultation, data acquisition and computational analysis.