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Woman snoring in bed.
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Research Feature
For much of her life, Sarah Gorman, 71, battled a mysterious illness that left her tired, sleepless, and unable to concentrate. When her symptoms first started in her 20s, she turned to doctors for help. They diagnosed her with depression and referred her to a psychiatrist, but Gorman soon rejected that diagnosis because, she said, she simply did...
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NHLBI in the Press
Two studies partly funded by NHLBI have shown remarkable results in the treatment of patients with cystic fibrosis who also have at least one copy of the Phe508del CFTR, the most common CF-causing mutation.
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NHLBI in the Press
Researchers have struggled to capture how mitochondrial DNA escapes the mitochondria—the energy powerhouse—in living cells. But now, a study published in the journal Science, provides an understanding of this process and could explain how inflammation occurs in autoimmune diseases.
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NHLBI in the Press
Researchers are reporting discovery of a previously unidentified autoinflammatory disorder that triggers mysterious fevers every few weeks. They found that the disorder involves mutations in the RIPK1 gene, which makes a key protein in the mediation of cell death and inflammation.
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NHLBI in the Press
The latest study conducted by NHLBI’s Prevention and Early Treatment of Acute Lung Injury (PETAL) Network concluded that administering high doses of vitamin D does not reduce mortality or morbidity in critically ill patients with vitamin D deficiencies.
image of bags of blood.
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News Release
Fresh red blood cell transfusions do not help critically ill children more than older cells NIH-funded finding may alter policies at hospitals where fresh red cells are preferentially used Researchers have found that transfusions using fresh red blood cells—cells that have spent seven days or less in storage—are no more beneficial than older red...
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NHLBI in the Press
Directly injecting living or dead heart stem cells into injured hearts and surrounding injured tissue triggers acute inflammation and wound healing-like properties in mice, according to a new study in Nature.
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NHLBI in the Press
Researchers identified mutations in the PfCRT protein, found in the malaria parasite’s digestive compartment, as the source of resistance to the frontline malaria drug piperaquine (or PPQ). Malaria affects over 200 million people every year around the globe.
Group of hands holding red ribbon stop drugs and HIV/AIDS awareness
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Research Features
Chris Camp recalls the early days of the HIV/AIDS epidemic, when being diagnosed as HIV positive was considered a virtual death sentence. Doctors had no medications that could really help. People with the disease often did not survive more than a year or two. Camp, now 63, says he personally lost more than 500 friends. Among them: his first husband...
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NHLBI in the Press
Fifty years of advancement into an ever-greater understanding of lung illnesses have whet the interest of the NHLBI’s Division of Lung Diseases (DLD) in precision medicine.
Senior hispanic man man testing breathing function by spirometry. Diagnosis of respiratory function in pulmonary disease.
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Research Feature
It is the fourth leading cause of death in the United States, affecting nearly 16 million people, but for many Americans, chronic obstructive pulmonary disease, or COPD, still remains a mystery. That’s why in 2017, at the request of Congress, the NHLBI led a year-long, multi-team effort to figure out what it would take to relieve the burden of this...
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NHLBI in the Press
Teens with a single ventricle heart defect significantly improved their capacity to sustain moderate exercise by taking an oral medication. The trial results, researchers say, represent a milestone in the care for those who have undergone the Fontan procedure, a palliative operation for this patient