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Research Feature
Activating a protein in red blood cells may improve anemia and alleviate acute episodes of severe pain for people living with sickle cell disease Swee Lay Thein, M.B., D.Sc., a senior investigator and chief of NHLBI’s Sickle Cell Branch, shares insight into a decade-long research journey that may lead to new ways to help people living with sickle...
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Statement
In large clinical trials conducted worldwide, full dose anti-coagulation (blood thinner) treatments given to moderately ill patients hospitalized for COVID-19 reduced the requirement of vital organ support—such as the need for mechanical ventilation. A trend in possible reduction of mortality was also observed and is being further studied. With...

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News Release
DNA-based “liquid biopsy” could help save lives and reduce health disparities Researchers have developed a blood test that could make it possible for doctors to detect—then quickly prevent or slow down—acute heart transplant rejection, a potentially deadly condition that occurs in the early months after a patient has received a donor heart. They...

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Media Availability
WHAT: Dietary Approaches to Stop Hypertension (DASH) has tied for first out of 39 diets for “Best Diets for Healthy Eating” and “Best Heart-Healthy Diets” in the 2021 Best Diets report from U.S. News & World Report. DASH, which builds nutrient-dense meals around whole grains, low-fat dairy products, vegetables, and fruits, and includes fish...

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News Release
Psoriasis, a chronic inflammatory skin disease, has long been known to increase the risk of cardiovascular disease, which includes heart attack and stroke. Now, researchers have identified a key culprit: the presence of metabolic syndrome (MetSyn), a condition that includes obesity, diabetes, high cholesterol, and hypertension, and is highly...

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Statement
Three clinical trial platforms working together to test the effects of full doses of anticoagulants (blood thinners) in COVID-19 patients have paused enrollment for one group of patients. Among critically ill COVID-19 patients requiring intensive care unit (ICU) support, therapeutic anticoagulation drugs did not reduce the need for organ support...

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Research Features
When the November 2020 news broke that two vaccines had proven to be highly effective in preventing COVID-19 or minimizing its impact, people everywhere began talking about seeing a light at the end of the tunnel. But many public health experts were talking, too, about another bright spot – the vast numbers of participants from racial and ethnic...

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News Release
NIH-funded study finds higher dose is not more effective at reducing serious flu complications in this high-risk group High-dose influenza (commonly known as flu) vaccines are no better than regular-dose influenza vaccines in reducing deaths and hospitalizations among patients with underlying heart disease, according to a large study publishing in...

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News Release
Updates to six key areas of asthma care focus on improving diagnosis, management and treatment The National Institutes of Health today announced 19 recommendations in six key areas of asthma diagnosis, management and treatment. The new guidance, published in the Journal of Allergy and Clinical Immunology, represents the first updates to federal...

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Media Advisory
WHAT: The National Heart, Lung, and Blood Institute (NHLBI) announces selection of Marishka Brown, Ph.D., as Director of the National Center on Sleep Disorders Research (NCSDR). Congress established the NCSDR in 1993 to coordinate sleep research throughout NIH and other federal agencies. Dr. Brown succeeds Michael Twery, Ph.D., who served as the...

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News Release
Using a life support machine to replicate the functions of the heart and lungs significantly improved the survival of people who suffered from out-of-hospital cardiac arrest, according to a new study published today in The Lancet. The treatment program involving the life support machine called extracorporeal membrane oxygenation (ECMO) proved so...