In large clinical trials conducted worldwide, full dose anti-coagulation (blood thinner) treatments given to moderately ill patients hospitalized for COVID-19 reduced the requirement of vital organ support—such as the need for mechanical ventilation. A trend in possible reduction of mortality was also observed and is being further studied. With...
A new study has found the addition of long-acting beta-agonist therapy to be the most effective of three step-up, or supplemental, treatments for children whose asthma is not well controlled on low doses of inhaled corticosteroids alone. The study was designed to provide needed evidence for selecting step-up care for such children and was supported...
Medical researchers are developing a new surveillance system to determine the number of patients diagnosed with a family of inherited blood disorders known as hemoglobinopathies, including sickle cell disease, thalassemias, and hemoglobin E disease. The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health is...
Scientists have devised a new computational model that can be used to reveal genetic regulatory elements responsible for development of the human heart and maintenance of its function. Although the teams focused on the heart, the computational method they developed is broadly applicable to other tissues, and was successfully used to identify...
New analyses from the Women's Health Initiative (WHI) confirm that combination hormone therapy increases the risk of heart disease in healthy postmenopausal women. Researchers report a trend toward an increased risk of heart disease during the first two years of hormone therapy among women who began therapy within 10 years of menopause, and a more...
The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has awarded four contracts totaling $23.6 million to begin preclinical testing of devices to help children born with congenital heart defects or those who develop heart failure. The four-year program is called Pumps for Kids, Infants, and Neonates...
In recognition of American Heart Month, the National Heart, Lung, and Blood Institute (NHLBI) and its heart disease awareness campaign—The Heart Truth— is reminding all American women that heart disease prevention remains critically important, despite that fact that awareness is at an all time high. More women than ever know that heart disease is...
A common lung condition, COPD (chronic obstructive pulmonary disease) diminishes the heart's ability to pump effectively even when the disease has no or mild symptoms, according to research published in the Jan. 21 issue of the New England Journal of Medicine. The study is the first time researchers have shown strong links between heart function...
This afternoon we lost one of the greatest scientists of our time, Marshall W. Nirenberg, Ph.D., to a long battle with cancer. Our deepest sympathies are with his wife, Myrna Weissman, Ph.D., other members of his family, and many friends and colleagues. Dr. Nirenberg first came to the National Institutes of Health (NIH) in 1957 at the age of 30 as...