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Scientists at the National Institutes of Health have identified a potential molecular target for reducing obesity-related inflammation. Researchers have known that overeating (that is, excess calorie consumption) by individuals with obesity often triggers inflammation, which has been linked to such diseases as asthma and Type 2 diabetes. In their...

In a study published online today in the New England Journal of Medicine , researchers found that cardiopulmonary resuscitation (CPR) administered by emergency medical services (EMS) providers following sudden cardiac arrest that combines chest compressions with interruptions for ventilation resulted in longer survival times and shorter hospital...

NIH-supported researchers are reporting more details on a landmark study that announced preliminary findings in September showing a lower blood pressure target can save lives and reduce the risk of cardiovascular disease in a group of non-diabetic adults 50 years and older with high blood pressure. Results of the Systolic Blood Pressure...

WHAT: An international team of scientists co-led by researchers from the National Heart, Lung, and Blood Institute (NHLBI) is reporting the discovery of nearly 1,500 age-related genes, most of which have not been previously identified. The study, one of the largest of its kind to explore genes associated with aging, could spark new insights into...

Lower blood pressure target greatly reduces cardiovascular complications and deaths in older adults More intensive management of high blood pressure, below a commonly recommended blood pressure target, significantly reduces rates of cardiovascular disease, and lowers risk of death in a group of adults 50 years and older with high blood pressure...

WHAT: Scientists now report a new way to assess cholesterol that shows promise for evaluating the increased heart attack risk observed in patients with psoriasis, a common inflammatory skin disease. The new technique measures the function of high-density lipoprotein (HDL), known as “good” cholesterol, rather than HDL cholesterol concentration. The...

In response to a request from the Congress, NIH is developing a 5-year NIH-wide Strategic Plan to advance its mission to support research in pursuit of fundamental knowledge about the nature and behavior of living systems, and the application of that knowledge to extend healthy life and reduce illness and disability. Senior leadership and staff...

A new study overturns longstanding scientific ideas regarding how energy is distributed within muscles for powering movement. Scientists are reporting the first clear evidence that muscle cells distribute energy primarily by the rapid conduction of electrical charges through a vast, interconnected network of mitochondria—the cell’s “powerhouse”—in...

WHAT: Scientists have identified a group of genetic mutations in patients with aplastic anemia, which likely will help doctors optimize treatment for this rare and deadly blood condition. The study, appearing in the New England Journal of Medicine , could lead to tailor-made treatment plans for aplastic anemia patients as part of the emerging...

Study opens door to new opportunities in medicine and research WHAT: Scientists have developed an efficient method of producing substantial quantities of RNA molecules with selectively labeled regions, paving the way for more advanced research and medical applications. RNA — DNA's lesser-known partner molecule — plays a significant role not only in...