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Adults who cut back on sleep for six weeks had increased markers of inflammation Getting a consistent good night’s sleep supports normal production and programming of hematopoietic stem cells, a building block of the body’s innate immune system, according to a small National Institutes of Health-supported study in humans and mice. Sleep has long...

About 20–40% of adults with COPD symptoms but who aren’t diagnosed with COPD use these types of long-lasting inhalers Researchers supported by the National Institutes of Health have found that dual bronchodilators – long-lasting inhalers that relax the airways and make it easier to breathe – do little to help people who do not have chronic...

Researchers at the National Institutes of Health have found that a novel blood test can be used to easily evaluate disease severity in patients with pulmonary arterial hypertension (PAH) and predict survivability. PAH is a rare, life-threatening condition that causes unexplained high blood pressure in the lungs. In early clinical studies, the...

Findings support personalized public health interventions to help close gaps Research supported by the National Institutes of Health shows that cardiovascular-related deaths have declined over the past two decades, but disparities remain. Researchers found that inequities are mostly driven by differences in race and ethnicity, geographic location...

A class of viruses known to cause severe diarrheal diseases – including the one famous for widespread outbreaks on cruise ships – can grow in the salivary glands of mice and spread through their saliva, scientists at the National Institutes of Health have discovered. The findings show that a new route of transmission exists for these common viruses...

Poor sleep is associated with a significantly increased risk of life-threatening flare-ups in people with chronic obstructive pulmonary disease , or COPD, according to a new study supported by the National Institutes of Health. The risk for these flare-ups – sudden bouts of worsening breathing – was 25% to 95% higher in people who experienced poor...

Potential curative therapies may help reduce the burden, but are also costly Americans ages 64 and younger with commercial health insurance who live with sickle cell disease (SCD) pay almost four times more in out-of-pocket medical costs over their lifetimes, a total of $44,000, compared to people living without the disease. And insurers pay $1.7...

NIH-funded study explains factors linked to increased risk for heart attack or stroke among women who have pregnancy problems related to high blood pressure Women who experienced complications related to developing high blood pressure, or hypertension, during pregnancy had a 63% increased risk for developing cardiovascular disease later in life...

Certain reproductive health events have been linked to increased risks for heart disease. But women and their doctors can do a lot to reduce those risks. Anybody who gets an annual checkup knows that heart health is often at the top of the list, which is why measuring blood cholesterol, blood sugar, and blood pressure is important. These and other...

A “bench-to-boardroom” program at NHLBI helps researchers bring to life new concepts, therapies, and devices, including an update on a familiar pump Few people think about what would happen if the main pumping chamber of their heart stops working – especially what options doctors may have to fix it. But Richard Smalling, M.D., Ph.D., has studied...