The U.S. Food and Drug Administration approved two new gene therapies to treat sickle cell disease — one a gene-editing and the other a gene-addition approach. Nearly 100,000 people in the United States — and millions worldwide — have been diagnosed with this painful, life-threatening genetic blood disease. To help explain the historic importance...
Among adults who received a pulmonary function test, a greater proportion of Black adults were reclassified as having reduced lung function if a race-neutral equation was used compared to a race-specific equation.
After following more than 4,000 adults with COPD for almost 10 years, researchers found those with extra mucus accumulating in their airways had an associated increased risk for dying early. These findings may advance research to identify targeted approaches for treatment.
Researchers found adding coronary artery calcium scores to 10-year heart disease risk calculators improved predictions for middle-aged to older adults, but polygenic risk scores, which provide general genetic insight, didn’t have the same effect.