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Research Feature
A cell-based look at how the body responds to immune threats may one day help researchers find better treatments for this major U.S. killer For more than a decade, researchers have known that a core component of human immune function – called complement – can influence how the body responds to immune threats. Now researchers from the NIH and around...
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Research Feature
Not so long ago, when doctors saw a patient with the inflammatory skin condition psoriasis, their first line of attack was to address the signs they could see—red, itchy, scaly patches, mostly on the knees, elbows, trunk and scalp. But research over the last several years is forcing a rethinking of the very nature of this common disease. Rather...
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Research Feature
Months ago, when news came flooding in about the dire toll the novel coronavirus can take on the body, so did the phone calls to Beth Kozel, M.D., Ph.D. A clinical geneticist in the Division of Intramural Research (DIR) at the National Heart, Lung, and Blood Institute (NHLBI), Kozel cares for adult and pediatric patients with rare connective tissue...
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Research Feature
Researchers supported by the National Institutes of Health have launched a key study to explore the safety and effectiveness of convalescent plasma in treating patients who have recently (within the last week) developed mild to moderate symptoms of COVID-19 disease. The study, which focuses on patients not yet hospitalized, comes on the heels of an...
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Research Feature
The coronavirus pandemic has caused tragedy and turmoil for millions of people around the world, but it has been particularly unkind to one group whose health journey is often overlooked: Those with sickle cell disease. A growing number of studies now suggest that people with this painful genetic blood disorder who also are infected with SARS-CoV-2...
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Research Feature
As the coronavirus pandemic continues to disrupt daily living, researchers are taking a closer look at one requirement for health that many people take for granted: sleep. And they’ve concluded, perhaps not surprisingly, that improving our sleep schedule and quality is an important part of coping with these stressful times and defending against...
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Research Feature
NHLBI expands access to diverse genetic data, creating more possibilities for personalized medicine It was a big moment nearly four years ago when NHLBI’s Trans-Omics for Precision Medicine program (TOPMed) released nearly 9,000 whole genomes to a limited group of researchers. The genomes—complete sets of people’s DNA—were the first the program had...
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Research Feature
A new smartphone app could be a boon for adolescents, young adults When the Food and Drug Administration (FDA) approved the drug hydroxyurea to help reduce the excruciating pain suffered by people with sickle cell disease, the health care community was hopeful. The year was 1998, and the prospect of a drug that could offer significant relief from...
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Research Feature
NHLBI-funded researchers tackle big questions with large study of patients hospitalized with COVID-19 The doctors on the front lines of the coronavirus pandemic may be aware of the health impacts that face survivors of mass shootings or natural disasters, but the highly contagious virus—one of the deadliest in history—is forcing them to grapple...
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Research Feature
In 2014 when the deadly Ebola virus was spreading like wildfire through parts of West Africa, Rear Admiral Richard Childs, M.D., led a team of physicians, nurses, engineers, and safety inspectors to Monrovia, Liberia to help treat the thousands of patients who had been infected. As the chief medical officer for the U.S. Public Health Service (USHPS...
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Research Feature
When doctors diagnosed Mary Douglas-Brown, 69, with breast cancer in 2004, she turned to her congregation at Pilgrim Rest Baptist Church in Washington D.C. for support, only to learn that it did not have a ministry to provide health and lifestyle resources that might help her through her ordeal. So she did what any determined churchgoer would do...