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Research Feature
The human genome was fully sequenced more than 20 years ago and is powering ways to predict, treat, and prevent cardiovascular disease As researchers study the genetic underpinnings of heart and vascular disease, they are creating new ways to screen, diagnose, and treat patients for a variety of heart conditions. Some are exploring how to better...
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Research Feature
NIH research continues to evaluate how blood thinners and anti-inflammatory medications may strengthen recovery at different points in the life of the virus W. Keith Hoots, M.D., director of the Division of Blood Disorders and Resources (DBDR) at the National Heart, Lung, and Blood Institute (NHLBI), shares insight into how treatments that break up...
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Research Feature
Severe blood clotting in patients has sent researchers in search of answers to optimize treatment and recovery As the virus that causes COVID-19 invades cells and replicates its code for infection, the body’s immune response fights back. However, for some people this can lead to extreme blood clotting – which can increase the risk for heart attack...
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Research Feature
Millions of people in America have been diagnosed with chronic obstructive pulmonary disease (COPD)—the umbrella term for emphysema and chronic bronchitis—and millions more have it and don’t know it. People in rural and other underserved communities are more likely to face higher rates of COPD and worse health outcomes from the disease. And for...
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Research Feature
For 33 years, the NHLBI’s Strong Heart Study has focused on learning why American Indians have one of the highest heart disease rates in the nation—almost double that of the general population. And during that time, it has made important discoveries – confirming, for example, that risk factors like diabetes, high blood pressure, and elevated...
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Research Feature
“Look at that! Life!” said Deidra Flowers-Williams, a sickle cell disease patient, as she held up a tube with stem cells donated by her sister, Tanisha Flowers. It was just minutes before doctors at the NIH Clinical Center would use the cells – extracted from her sister’s bone marrow – for a transplant they hoped would cure the devastating blood...
Credit: Hemex Health
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Research Feature
About 20 years ago, researchers excitedly announced the coming of so-called lab-on-chip devices that could revolutionize medicine. At the time, people marveled at the possibilities: The devices would take the capabilities of a large biochemistry lab and shrink them to a platform the size of a cell phone or smaller. With help from a portable scanner...
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Research Feature
When COVID-19 restrictions closed research laboratories across the country, it meant Erik Kimble, M.D.’s hematology and oncology training came to a virtual crawl. Not surprisingly, Kimble, who completed medical school in Mexico at the height of the swine flu pandemic, was overwhelmed yet again with uncertainty. He spent months preparing for his...
Credit: Kem Sochacki, Ph.D. NHLBI, DIR
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Research Feature
Every day researchers across NIH use an array of imaging technologies and equipment to help them make new scientific discoveries. However, over the last 10-15 years, a massive explosion in the use of Cryo-Electron Microscopy (cryo-EM) – a technique that allows the direct imaging of proteins within cells – has revolutionized the way scientists do...
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Research Feature
For nearly 15 years, the Cardiothoracic Surgical Trials Network (CTSN) has played a key role in designing and conducting collaborative clinical trials aimed at improving surgical treatments for cardiovascular disease, the nation’s leading cause of death. CTSN’s efforts to learn more about these treatments – valve replacements, bypass procedures...
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Research Feature
At St. Louis Children’s Hospital in Missouri, a 12-year-old boy waiting in an exam room held a tablet as he scrolled through a trivia game about sickle cell disease (SCD) – an inherited blood disorder that had brought him to the hospital for a regular visit. As he played the game, he won a badge each time he answered a question right. But happily...