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Senior hispanic man man testing breathing function by spirometry. Diagnosis of respiratory function in pulmonary disease.
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Research Feature
It is the fourth leading cause of death in the United States, affecting nearly 16 million people, but for many Americans, chronic obstructive pulmonary disease, or COPD, still remains a mystery. That’s why in 2017, at the request of Congress, the NHLBI led a year-long, multi-team effort to figure out what it would take to relieve the burden of this...
mother hugging down who has down syndrome
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Research Feature
Studies target heart, lung, and sleep disorders associated with condition Each year, about 5,300 babies are born in the United States with Down syndrome, a genetic disease that is associated with intellectual and physical challenges. People with the condition have a high risk of heart defects, pulmonary hypertension, sleep apnea, gastrointestinal...
Group of Native American's hula dancing
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Research Feature
Brandie Taylor is watching her teenage son, Hunter Banegas, grow into a man. She is proud of his talent and his embrace of Kumeyaay Bird Singing, which is performed at traditional gatherings of their tribe, the Iipay Nation of Santa Ysabel, near San Diego, Calif. But 13 years ago, a future filled with song—a future with Hunter—seemed doubtful. When...
About 1 in every 16,300 Hispanic babies is born with sickle cell disease
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Research Feature
En el 2000, Mercy Mendoza, a los 3 años, languidecía con una enfermedad misteriosa. Su abuela, desesperanzada, compró un sitio donde enterrarla en el pueblito de Honduras donde vivían. La hinchazón, el dolor y la inmovilidad estaban erosionando rápidamente su salud. Finalmente, un médico que había estudiado en los Estados Unidos reconoció su...
About 1 in every 16,300 Hispanic babies is born with sickle cell disease.
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Research Feature
In 2000, a mysterious disease was making 3-year-old Mercy Mendoza so ill that her grandmother bought a burial plot for her in the little town in Honduras where they lived. Swelling, pain, and immobility were fast eroding her health. Finally, a doctor who had been trained in the United States recognized her condition: It was sickle cell disease, an...
Pregnant woman at doctor's office having pressure measured.
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Research Feature
If a woman is pregnant and chronic high blood pressure is seriously high, doctors typically don’t debate what to do. They treat it—and fas t—mainly to minimize the risk for strokes and other potentially deadly cardiovascular events. But what if the woman’s chronic high blood pressure is considered, well, mild—say, less than 160/105 mm Hg? As it...
pregnant woman sleeping
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Research Feature
Poor sleep may seem like a normal fallout of pregnancy, but research shows it can be a pernicious problem, with long-term ill effects on a woman’s cardiovascular health. Pregnant women who suffer from sleep-disordered breathing, particularly sleep apnea, are at higher risk for both gestational diabetes and hypertensive disorders of pregnancy, the...
Microscope view of the lungs
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Research Feature
Might pave the way for new and improved treatments for a wide variety of respiratory diseases Maps may be great tools for helping you find your way around unfamiliar places, but in the future, a new type of map well might help save your life. Welcome to the Molecular Atlas of Lung Development Program, or LungMAP, a historic effort to help...
Photograph of Jennelle Stephenson work with a nurse at the National Institutes of Health Clinical Center.
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Research Feature
When CBS’s 60 Minutes aired the compelling story of a Florida woman whose severe sickle cell disease symptoms were alleviated with a cutting edge gene therapy technique, people listened. A lot of them. The treatment happened at the National Institutes of Health, and since the showcasing of its dramatic success, NIH has been responding to scores of...
3D models of infant hearts
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Research Feature
Advances in Congenital Heart Disease Research Are Helping Kids Thrive In 1949 when the National Heart Institute—not yet the National Heart, Lung, and Blood Institute—began awarding research grants in pediatric cardiovascular disease, among the first was to a surgeon named Alfred Blalock, M.D. With his colleagues at Johns Hopkins University—Helen...
A man looks at old pictures with his son
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Research Feature
Visit highlights enormous strides in congenital heart disease research Fifty years ago, amid national protests over the war in Vietnam and giddy anticipation of man’s first walk on the moon, Gladys and Thomas Kaminski drove up to the gates of the National Institutes of Health, holding out hope for a miracle. Tom Kaminski, 7, with his father in 1969...
Dr. Oyebola in the lab.
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Research Feature
A conversation with Dr. Kolapo Oyebola It is not lost on Kolapo Oyebola, Ph.D., that half the sickle cell disease cases worldwide can be found in his native Nigeria. This tragic fact, said the National Institutes of Health (NIH) postdoctoral fellow, has long been top of mind—and he is bent on doing something about it. Something big. He wants to...
Chicken and beef meat in foam packaging
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Research Feature
Detailed comparison suggests plant proteins are better for the heart If you’re among the millions of Americans who are eating more chicken because you think it has less fat and is better for your heart than a good ol’ hot dog or burger, researchers are offering some new food for thought. In a study that could debunk years of conventional wisdom,...
African american grandmother happy after working out
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Research Feature
If you are a woman over 60, move more. Move often. Break those long sitting bouts. Why? Literally, every time you twist, turn, walk, or stand counts towards improving your cardiovascular health. That’s the good-news message from two recently published studies on the cardiovascular effects of sedentary behaviors and light physical activity in older...
T. Morgan Dixon (left) and Vanessa Garrison, founder of GirlTrek.
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Research Feature
Vanessa Garrison and T. Morgan Dixon know a ton about fitness. Between the two, they’ve hiked, walked, biked, and run more miles than they can ever begin to count. But nine years ago, when the two college buddies founded GirlTrek, now the largest public health nonprofit for African American women and girls in the United States, their first thought...
Newborn blood spot (heel prick) test (the Guthrie' test). A physician performing the pinprick puncture in one heel of a newborn to collect their blood to screen for inborn errors of metabolism.
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Research Feature
Soon after birth, a baby in the United States is tested for sickle cell disease, the often-devastating genetic blood disorder affecting more than 100,000 Americans and 20 million of people worldwide. If positive, that newborn typically begins a course of treatment that can greatly prolong life and help stave off complications of the disease. But in...
Illustration of human head with brain and pills.
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Research Feature
The story of the U.S. opioid crisis is often told through numbers. And for many that makes sense, because the numbers are staggering: More than two million Americans suffer from opioid use disorder (OUD), a serious, but treatable chronic illness that claims the lives of more than 130 people every day. Many with OUD carry another burden, however:...
Image of the cover of the January edition of the Transfusion journal
Credit: Transfusion journal
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Research Feature
Every two seconds someone in the United States needs blood. Five million people receive a blood transfusion every year in the U.S. In a country where blood is perennially in short supply, it is the most common medical procedure of all. Yet giving to a blood bank is not always a slam dunk—some people get turned away because of strict rules meant for...
Cure Sickle Cell.
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Research Feature
When the NHLBI announced the launch of the Cure Sickle Cell Initiative on September 13, many in the sickle cell disease community responded with enthusiasm. Patients, family members, and advocates took to social media and other channels to say they are ready to do their part, starting with spreading the news about the initiative to their neighbors,...