Denis B. Buxton, Ph.D.
An NIH-supported study in mice suggests that new heart cells arise from pre-existing heart cells and that the renewal process slows with age. The findings may lead to improved regenerative therapy for people with heart damage.
In an NHLBI-funded study. that could help advance the field of regenerative medicine for years to come, the Interdisciplinary Stem Cell Institute at the Miller School has found that mesenchymal stem cells, whether from patients or donors, can treat people whose hearts were previously damaged and scarred after a heart attack.
An international team of researchers discovered that a heart attack doesn't just damage heart muscle tissue by cutting off its blood supply, it also sets off an inflammatory response that worsens underlying atherosclerosis, actively increasing the risk for a future heart attack. Study results were published in the journal Nature.
Cell therapy approaches have great potential for preventing the development of heart failure after myocardial infarction (heart attack) and for treating patients with existing heart failure.
This review summarizes recent progress in the application of molecular imaging to aortic aneurysm in animal models and patients.
The National Institutes of Health (NIH) will hold a Technology Assessment Conference (TAC) to look at barriers and opportunities to developing systems for implant retrieval analysis and data banking. The TAC will be conducted January 10-12, 2000 in the Natcher Conference Center on the NIH campus in Bethesda, Maryland.
Heart bypass patients treated with a timed-release capsule of a substance that promotes the growth of new blood vessels showed evidence of improved blood supply and heart function, according to a study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.
"Growing" blood vessels, a strategy called angiogenesis, is a promising experimental treatment for blocked arteries in bypass surgery patients for whom surgery alone would not adequately restore blood flow to the heart.