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mouse vein graft model showing endothelial cells
March 12, 2014

Researchers find reason why many vein grafts fail

National Institutes of Health researchers have identified a biological pathway that contributes to the high rate of vein graft failure following bypass surgery. Using mouse models of bypass surgery, they showed that excess signaling via the Transforming Growth Factor Beta (TGF-Beta) family causes the inner walls of the vein become too thick, slowing down or sometimes even blocking the blood flow that the graft was intended to restore.

February 24, 2014

NIH releases comprehensive new data outlining Hispanic/Latino health and habits

A comprehensive health and lifestyle analysis of people from a range of Hispanic/ Latino origins shows that this segment of the U.S. population is diverse, not only in ancestry, culture, and economic status, but also in the prevalence of several diseases, risk factors, and lifestyle habits. These new findings have been compiled and published as the Hispanic Community Health Study Data Book: A Report to the Communities.

February 24, 2014

NIH publica nuevos datos sobre la salud y hábitos de hispanos y latinos

Un análisis integral de la salud y estilo de vida de personas de una amplia gama de orígenes hispanos y latinos muestra que este segmento de la población de los Estados Unidos es diversa, no sólo en la ascendencia, la cultura, y la situación económica, sino también en la prevalencia de varias enfermedades y sus factores de riesgo, y los hábitos de estilo de vida.

February 11, 2014

NIH study seeks to improve asthma therapy for African-Americans

Researchers will enroll around 500 African-American children and adults who have asthma in a multi-center clinical trial to assess how they react to therapies and to explore the role of genetics in determining the response to asthma treatment. This new clinical study, which will take place at 30 sites in 14 states, is aimed at understanding the best approach to asthma management in African-Americans.

November 19, 2013

Genetic data does not improve anticoagulation control with warfarin

Combining genetic data with clinical information to determine the initial dosage of the blood thinner warfarin, used to prevent blood clots in the circulatory system, was no more effective in achieving stable anticoagulation than using only clinical information, according to a National Institutes of Health-funded clinical trial. In addition, the study found that in African-Americans, anticoagulation control was lower in the genetics-based approach compared to the clinically-based method.

November 19, 2013

Genetic data does not improve anticoagulation control with warfarin

Combining genetic data with clinical information to determine the initial dosage of the blood thinner warfarin, used to prevent blood clots in the circulatory system, was no more effective in achieving stable anticoagulation than using only clinical information, according to a National Institutes of Health-funded clinical trial. In addition, the study found that in African-Americans, anticoagulation control was lower in the genetics-based approach compared to the clinically-based method

November 18, 2013

Renal artery stents lead to similar outcome versus medication-only

A commonly used stenting procedure to treat plaque build-up in the renal artery appears to offer no significant improvement when added to medication-based therapy, according to results from a National Institutes of Health-funded study. The narrowing and hardening of one or both renal arteries, known as renal artery stenosis, occurs in 1 to 5 percent of people who have high blood pressure, or hypertension.

November 18, 2013

Valve repair or replacement offers similar outcomes for severe heart valve disease

Repair or replace? Consumers often ask this question when considering faulty cars, appliances, or other equipment. A new clinical study has now addressed this question for a serious medical decision: how to treat ischemic mitral regurgitation (IMR), a condition in which blood backflows into the heart because the mitral valve becomes leaky after a heart attack. The study compared the two surgical options –re-tightening the leaky mitral valve or replacing it with a prosthetic –and found no significant differences in patient outcomes after a year.

November 15, 2013

NIH survey identifies barriers to effective patient-provider dialogue about COPD

Lack of communication between patients and health care providers about chronic obstructive pulmonary disease (COPD) remains a major barrier to diagnosis of this disease, according to the results of a Web-based survey released today by the National Heart Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

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