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May 19, 2014

Common treatment for patients with chronic, progressive lung disease found to be ineffective

A drug used to treat patients with mild to moderate lung damage from the disease idiopathic pulmonary fibrosis (IPF) is no better than placebo for preserving lung function, according to a study supported by the National Institutes of Health.
The finding is in the final report of a clinical trial called Prednisone, Azathioprine, and N-Acetylcysteine: A Study That Evaluates Response in Idiopathic Pulmonary Fibrosis (PANTHER-IPF).

May 18, 2014

Vitamin D supplementation does not reduce asthma treatment failure in people with low Vitamin D, but some benefits suggested.

Supplementing inhaled corticosteroids (ICS) with vitamin D does not reduce the rate of treatment failure in patients with asthma and vitamin D insufficiency, finds a new NIH-funded study. The Vitamin D Add-on Therapy Enhances Corticosteroid Responsiveness in Asthma (VIDA) trial randomized 408 adults with low vitamin D and mild/moderate asthma to receive the ICS ciclesonide supplemented with either high-dose vitamin D3 or placebo.

May 18, 2014

NIH-funded studies find statins provide no benefit to COPD, ARDS outcomes

Statin therapy does not prevent exacerbations of chronic obstructive pulmonary disease (COPD) or lower mortality from acute respiratory distress syndrome (ARDS), report two studies that rigorously tested the benefit of the cholesterol-lowering drugs on outcomes in the lung diseases.

May 13, 2014

Asthma Awareness Month 2014: NIH continues its commitment to asthma research

May is Asthma Awareness Month, and the National Institutes of Health emphasizes the scientific progress being made in asthma research, from basic science, such as how lung cells work, to clinical trials on current and future treatments for the disease. NIH-led research includes studies of environmental factors, how the body’s own defense system plays a role, and the microbiome — all the microbial organisms that live in and on the human body.

April 9, 2014

Drug does not improve set of cardiovascular outcomes for diastolic heart failure

A drug that blocks the action of a key hormone did not significantly improve a set of cardiovascular outcomes for patients with diastolic heart failure, a condition in which the heart is stiffer than normal and has problems filling with blood, according to a study supported by the National Institutes of Health.

March 31, 2014

HIV-Infected Men at Increased Risk for Heart Disease, Large Study Finds

The buildup of soft plaque in arteries that nourish the heart is more common and extensive in HIV-infected men than HIV-uninfected men, independent of established cardiovascular disease risk factors, according to a new study by National Institutes of Health grantees. The findings suggest that HIV-infected men are at greater risk for a heart attack than their HIV-uninfected peers, the researchers write in Annals of Internal Medicine.

mouse vein graft model showing endothelial cells
March 12, 2014

Researchers find reason why many vein grafts fail

National Institutes of Health researchers have identified a biological pathway that contributes to the high rate of vein graft failure following bypass surgery. Using mouse models of bypass surgery, they showed that excess signaling via the Transforming Growth Factor Beta (TGF-Beta) family causes the inner walls of the vein become too thick, slowing down or sometimes even blocking the blood flow that the graft was intended to restore.

February 24, 2014

NIH releases comprehensive new data outlining Hispanic/Latino health and habits

A comprehensive health and lifestyle analysis of people from a range of Hispanic/ Latino origins shows that this segment of the U.S. population is diverse, not only in ancestry, culture, and economic status, but also in the prevalence of several diseases, risk factors, and lifestyle habits. These new findings have been compiled and published as the Hispanic Community Health Study Data Book: A Report to the Communities.

February 24, 2014

NIH publica nuevos datos sobre la salud y hábitos de hispanos y latinos

Un análisis integral de la salud y estilo de vida de personas de una amplia gama de orígenes hispanos y latinos muestra que este segmento de la población de los Estados Unidos es diversa, no sólo en la ascendencia, la cultura, y la situación económica, sino también en la prevalencia de varias enfermedades y sus factores de riesgo, y los hábitos de estilo de vida.

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