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May 16, 2017 : JAMA

An editorial by NHLBI director, Gary Gibbons, M.D. and colleagues, published by JAMA discusses the findings of a study in the journal about the geographic variation in cardiovascular mortality in the United States. The findings “serve as a critical reminder to challenge clinicians, investigators, and public health leaders to imagine a future in which an individual’s risk of cardiovascular death is no longer determined by “the place” he or she was born or resides and no longer prevents pursuing a healthy and fulfilling life,” said the authors.

Reuters: U.S. heart disease deaths drop but wide variation by county remains

American Heart Association News: Heart disease, stroke death rates vary widely depending on where you live

HealthDay: Heart Health Might Be a Matter of Geography

Becker’s Hospital Review: Geography matters for heart disease deaths, study shows

May 16, 2017 : U.S. News & World Report

High-dose iron pills do not improve exercise capacity in people with a certain type of heart failure frequently marked by iron deficiency, researchers are reporting.  In a study that measured exercise capacity among 225 patients with heart failure with reduced left ventricular ejection fraction, the researchers found no significant difference between those who received iron pills and those who received placebo after 16 weeks of treatment. The study, published in JAMA, is partly funded by NHLBI.

Medical Xpress: High-dose iron pills do not improve exercise capacity for heart failure

May 10, 2017 : Medical Xpress

Researchers are reporting that bacteria in the gut may contribute to the formation of cerebral cavernous malformations (CCMs), clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures.  The researchers suggest that altering the gut bacteria in people with CCMs may provide a promising treatment for this brain disease. Their study, which appeared in Nature, was partly funded by NHLBI.

May 3, 2017 : Nature

A study partly funded by NHLBI details the development of blood vessels. The authors think that the finding, published in Nature(link is external)shows pathways for new treatments of cardiovascular diseases and cancer. 

Health Canal(link is external)

Technology.org(link is external)

YaleNews(link is external)

Medical Xpress

May 2, 2017 : Cell Metabolism

Researchers led and partly funded by NHLBI have identified an enzyme that could help in the continuous battle against mid-life obesity and fitness loss. Reported in Cell Metabolismthe discovery in mice could upend current notions about why people gain weight as they age, and could one day lead to more effective weight-loss medications.   

May 1, 2017 : Nature

A research team partly funded by NHLBI found that stem cell lines grown in laboratories often acquire genetic mutations that could increase the risk of cancer in patients receiving transplants. The study was published in Nature.

 

 

The Scientist Magazine: Cell Lines Gain Cancer-Related Mutations 

 

 

April 27, 2017 : Genetic Engineering & Biotechnology News

Researchers have identified a potential new target in the mitochondria (the cell's powerhouse) for fighting heart disease.  In studies using mice, the scientists showed that the exit of calcium from mitochondria in heart cells plays a key role in normal heart function and that boosting calcium transport might help limit the severity of heart disease. Their study, published in Nature, was supported by NHLBI.  

April 27, 2017 : The New York Times

Consuming artificially sweetened soft drinks, such as diet sodas, appears to increase the risk of strokes and dementia, reports a study in the journal Stroke. The researchers used data from the NHLBI’s Framingham Heart Study.

Forbes: Why Is Diet Soda So Bad For Your Brain?

Science News: Regular Consumption of Sugary Beverages Affects Brain

Psych Central: Soda Linked to Faster Brain Aging

Cosmopolitan: Drinking Diet Soda Is Linked to Increased Stroke and Dementia Risk, Study Finds

wtop: Study: Drinking diet soda linked to stroke, dementia risk

Rhode Island Public Radio: New Study Says Diet Soda Linked To Stroke, Dementia

More coverage

April 27, 2017 : Cardiology Magazine

"It has been terrific to watch my patients grow up over the years, and watch the grace with which their parents accommodate the challenges of pediatric heart disease," said pediatric cardiologist Gail Pearson, MD, ScD, FACC, in an interview with Cardiology magazine. Pearson, associate director of the NHLBI Division of Cardiovascular Sciences and director of the Adult and Pediatric Cardiac Research Program, spoke about her career and NHLBI’s investment in pediatric cardiovascular research.

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