Researchers, with support from the National Heart, Lung, and Blood Institute, suggest that sleep deprivation may be a contributing factor to the nation’s childhood obesity problems. The study, which appeared in the Journal of Sleep Research, found that young children who did not sleep for long enough each night were at higher risk of overeating.
NHLBI In The News
Filter News Mentions
Researchers with the Consortium on Asthma among African-Ancestry Populations in the Americas (CAAPA) study noted significant differences when compared to other genomic databases that focused on European ancestry. The findings, based on the NHLBI-supported CAAPA study, appeared in Nature Communications. The researchers suggest that personalized medicine treatments based on data using databases focused on European ancestry may not be as effective for other populations.
Researchers involved with the NHLBI-supported Consortium on Asthma among African-Ancestry Populations in the Americas (CAAPA) study found notable genetic variation among the genomes of individuals depending on how their ancestors came to the Western Hemisphere. The findings, which appear in Nature Communications, could serve as a resource for creating genetic treatments for individuals of African ancestry.
In African Americans, a higher resting heart rate may mean greater risk of death or hospitalization for heart failure, a new study indicates. Researchers have already shown that an increased resting heart rate is associated with worse outcomes in mostly white populations, but its significance in African Americans has been unclear until now. A “resting” heart rate is measured when a person is sitting or lying down. The study, partly funded by NHLBI, was published in JAMA Cardiology.
Researchers are reporting new insight into how the body protects itself against dangerous arrhythmias, or irregular heart rhythms, that can accompany fever. In lab studies, they showed that mice lacking a certain protein called FHF2 experience abnormal heart rhythms as their body temperature slightly increases and that rhythms return to normal when body temperature is returned to normal. The finding demonstrates that FHF2 plays a key role in protecting against irregular heart rhythms and suggests that therapies that target the protein may help control heart rhythm during fever-induced arrhythmias and fever-induced seizures, the researchers say. The study, partly funded by NHLBI, appeared in Nature Communications.
Researchers are reporting new evidence that an increase in the amount of belly fat, especially “hidden fat” deep in the gut, is associated with a higher risk of developing heart disease. The study also demonstrated that the density of stomach fat is as important as how much fat you have. In particular, the researchers found that lower density abdominal fat was associated with a higher risk for heart disease. The six-year study included more than 1,000 adults. It was published in the Journal of the American College of Cardiology and funded by the National Heart, Lung, and Blood Institute.
Researchers are reporting new evidence that drinking tea is good for the heart. In the study, the researchers evaluated more than 6,000 participants from the Multi-Ethnic Study of Atherosclerosis (MESA), which is sponsored by the National Heart, Lung, and Blood Institute (NHLBI). They found that adults who drank at least one cup of tea per day had a slower progression of coronary artery calcium (a marker for subclinical heart disease) and a 29 percent lower risk of cardiovascular events, including heart attack and stroke, compared to adults who did not drink tea. The study, funded by NHLBI, was published in The American Journal of Medicine.
Researchers are reporting that understanding the evolutionary history of a protein may help scientists engineer better protein-based drugs for treating a variety of diseases. The research team explored a technique called “ancestral sequence reconstruction” or ASR, which involves using genetic sequences from a variety of animals to reconstruct possible ancestral sequences for a protein in early mammals. Using this information, they then tweak a human form of the protein to try to improve its properties. As proof of concept, they used this approach to make a more stable and potentially more effective form of human factor VIII, a blood clotting protein that is deficient in the inherited bleeding disorder hemophilia A. Their study, partly funded by NHLBI, was published in Nature Biotechnology.
Smoking can permanently damage DNA in a way that contributes to the development of smoking-related illnesses, according to a new study. The findings could reveal an individual’s smoking history and help identify potential targets for therapy, the researchers note. Their study is published in the journal Circulation: Cardiovascular Genetics, a publication of the American Heart Association. It was funded by the National Heart, Lung, and Blood Institute.
A new study indicates that wearable fitness trackers don’t seem to help people lose more weight in comparison to dieters who are not using the devices. The study, published in the Journal of the American Medical Association, was funded by the National Heart, Lung, and Blood Institute.