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News Release
Results from NIH-funded trial could extend patients’ well-being Teenagers born with a single working ventricle of the heart—a rare defect that cannot be completely corrected—showed a significant improvement in their ability to sustain moderate exercise after treatment with udenafil, a drug that helps improve blood flow, according to a new study...
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Research Features
Collaborative learning: Innovative research tool helps improve outcomes for congenital heart defects
Congenital heart defects have long posed great risks for the 2.5 million Americans who currently live with them. Now this most common of birth defects has become the focus of an innovative research model that could mean a brighter, healthier future for many children born with this often life-threatening condition. The model, which already has been...
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News Release
Scientists have confirmed the role of a set of gene mutations in the development of congenital heart disease and simultaneously discovered a link between them and some neurodevelopmental abnormalities in children. These abnormalities include cognitive, motor, social, and language impairments. “The risk of developing neurodevelopmental disabilities...
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Research Feature
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Research Feature
Nine studies focus on heart, lung, and blood diseases The National Institutes of Health has funded nine new studies that will develop induced pluripotent stem cells , or iPS cells, from patients with genetic variations that have been associated with coronary artery disease, pulmonary hypertension, clotting disorders, diabetes, and other conditions...
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Research Feature
The heart is the first organ to form and begin working in humans. More than two decades of research have told us a lot about normal heart development. New diagnostic tools such as fetal echocardiography now allow doctors to find heart defects during pregnancy. In 1950, a child born with a congenital heart defect had only a 20 percent chance of...