NHLBI IN THE PRESS
NHLBI-funded researchers identify potential new target for treating diabetes, heart disease

An NHLBI-funded study has identified a potential new target for treating type 2 diabetes and heart disease. In studies using obese mice, researchers showed that a liver enzyme called DPP4 appears to trigger inflammation in abdominal fat and increase insulin resistance. Blocking the liver enzyme could lessen inflammation and insulin resistance, researchers say. The study appeared in Nature.