NHLBI IN THE PRESS

The Unexpected Way Genes Can Double Heart Disease Risk

Medical instrument hanging from tabel.

Researchers funded by NHLBI found that a gene mutation called clonal hematopoiesis of indeterminate potential (CHIP) showed a higher rate of heart disease, according to a paper published in The New England Journal of Medicine. People do not inherit the CHIP mutations, instead, they accumulate over time from the exposure to things that damage DNA.

Media Coverage

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Time
  • The Unexpected Way Genes Can Double Heart Disease Risk
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    Medscape
  • Changes in Peripheral Blood Cells Linked to Increased CHD
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    Healio
  • Clonal hematopoiesis of indeterminate potential increases CHD risk
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    MedpageToday
  • CHIP May Connect Age, Atherosclerosis, and CHD
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    GenomeWeb
  • Cardiovascular Disease Risk Is Increased by Aging-Related Mutations in Blood Cells
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    DoctorsLounge
  • Clonal Hematopoiesis Linked to Coronary Heart Disease
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    The Stem Cellar
  • Cancer-causing mutations in blood stem cells may also link to heart disease
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    The New England Journal of Medicine
  • Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease