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Unrelated Allogeneic Cord Blood Banking and Transplant Forum

August 14-15, 2000
Masur Auditorium, Building 10, NIH, Bethesda, MD

Objectives
This forum will provide an opportunity to discuss unrelated allogeneic placental/umbilical cord blood transplant data, the procedures used by placental cord blood banks, and translational research needs.

DAY 1-August 14, 2000
8:00 a.m.             Welcome-Opening Remarks                                   NHLBI and CBER
8:05 a.m.              Introduction & Goals of Workshop                        Liana Harvath

SESSION 1.     UNRELATED ALLOGENEIC CORD BLOOD BANKS
       Co-Moderators - Joanne Kurtzberg &  Ellen Lazarus

8:15 a.m.              NYBC                                                                  Cladd Stevens
8:45 a.m.              COBLT                                                                 John Fraser
9:15 a.m.              St. Louis                                                                Donna Wall
9:45 a.m.              ARC                                                                      Tom Lane
10:15- 10:45 a.m.                 Break
10:45 a.m.            NMDP                                                                   Dennis Confer
11:15 a.m.            NETCORD                                                            Peter Wernet
11:45 a.m.            Nucleated RBCs                                                     Peter Wernet
12:00 p.m.            Transient Warming                                                  Phil Coelho
12:15 p.m.             Alberta                                                                   John Akabutu

12:30 -1:30 p.m.             Lunch

1:30 p.m.            Discussion: What differences, if any, are important?

SESSION 2.     PERFORMING THE SEARCH
       Moderator- Carolyn Hurley

2:45 p.m.             HLA, Search Determinants, & Finding a Match        Carolyn Hurley
3:00 p.m.             New York Blood Center                                          Pablo Rubinstein
3:20 p.m.             NMDP                                                                    Dennis Confer
3:40 p.m.             COBLT                                                                   Shelly Carter
3:40 - 4:00 p.m.         Break
4:00 p.m.             NETCORD                                                              Peter Hakenberg
4:20 p.m.             Transplant Center Perspective                                    Joanne Kurtzberg

4:30 p.m.            Discussion: Building Bridges Between Banks & Transplant Centers

DAY 2-August 15, 2000

SESSION 3.    TRANSPLANT OUTCOME ANALYSIS
    Moderator-Joanne Kurtzberg

8:00 a.m.             NYBC                                                                       Pablo Rubinstein
8:30 a.m.             Consolidated Data of Duke and Minnesota                 John Wagner
9:00 a.m.             St. Louis Experience                                                   Donna Wall
9:30 a.m.             Adult experience                                                         Mary Laughlin
10:00 - 10:30 a.m.        Break
10:30 a.m.            Japanese Experience                                                  Tsuneo Takahashi

11:00 a.m.           Discussion: Can we define an acceptable unit for transplant?

12:00 - 1:00 p.m.         Lunch

SESSION 4.    EX VIVO EXPANSION
     Moderator- Adrian Gee

1:00 p.m.             Expansion in bags                                                        Ian McNeice
1:20 p.m.             Expansion in a bioreactor                                             Joanne Kurtzberg
1:40 p.m.             Stromal Factors                                                           Catherine Verfaillie

2:00 p.m.            Discussion: What do we need to know?

2:15 - 2:40 p.m.             Break

SESSION 5.    WHAT IS A STEM CELL?
      Moderator-Hal Broxmeyer

2:40 p.m.             Introduction and Overview                                          Hal Broxmeyer
3:00 p.m.             Comparing UCB and BM Stem Cells                          Esmail Zanjani
3:20 p.m.             Potential New Markers:  ADHase                               Clay Smith
3:40 p.m.             Potential New Markers:  FRIL                                    Jeff Moore
4:00 p.m.             Importance of CFU-Meg                                            John Adamson
4:20 p.m.             Correlation of CD34+ Cells with CFU                        Jan Visser

4:40 p.m.            Discussion: Correlation with Outcome?

5:00 p.m.            Brief Summary and Future Directions

Sponsors
National Heart, Lung, and Blood Institute, NIH
Center for Biologics Evaluation and Research, FDA

Contacts
Dr. LeeAnn Jensen, 301 435-0066, E-mail: jensenl@nhlbi.nih.gov
Dr. Liana Harvath 301 435-0065,  E-mail: harvathl@nhlbi.nih.gov
Ms. Kathy Brasier, 301 435-0075, E-mail:  brasierk@nhlbi.nih.gov
Ms. Jillian Brown, 301 592-8600, E-mail:  jbrown@prospectassoc.com

For information on nearby hotels, please contact Jillian Brown of Prospect Associates.

Written material and requests to make oral presentations should be sent to Dr. LeeAnn Jensen, 6701 Rockledge Drive, Bethesda, MD  20892-7950; FAX (301) 480-0868; e-mail jensenl@nhlbi.nih.gov by August 4, 2000.

If you need special accommodations due to a disability, please contact Dr. Jensen at (301) 435-0066 least 7 days in advance.

Transcripts:  Transcripts of the workshop may be requested in writing from the Freedom of Information Office (HFI-35), Food and Drug Administration, 5600 Fishers Lane, rm. 12A-16, Rockville, MD 20857, approximately 15 working days after the workshop at a cost of 10 cents per page.

REGISTRATION
Seating is limited so please register early.  Complete the registration information below and fax to Jillian Brown, Prospect Associates at 301 593-9433 or e-mail requested information to jbrown@prospectassoc.com.  There is no registration fee for the workshop.

Registration at the site will be done on a space available basis on the day of the workshop beginning at 7:30 a.m.

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