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Obesity Hypoventilation Syndrome

Obesity hypoventilation syndrome, also known as Pickwickian syndrome, is a breathing disorder that causes you to have too much carbon dioxide and too little oxygen in your blood. It affects some people who have obesity.

Healthy Lifestyle

Overweight and Obesity

Overweight and obesity are chronic conditions that raise the risk of serious health problems, including heart disease and diabetes.




A pacemaker is a small device that sends electrical pulses to help the heart beat at a normal rate and rhythm.


Peripheral Artery Disease

Peripheral artery disease, or PAD, is a condition in which a sticky substance called plaque builds up in the arteries that carry blood away from the heart to other parts of the body.

Healthy Lifestyle

Physical Activity and Your Heart

Physical activity is any body movement that works your muscles and requires more energy than resting. Being physically active is one of the best ways to keep your heart and lungs healthy.


Platelet Disorders

Platelet disorders are conditions in which the number of platelets in your blood is either too low or too high, or your platelets don’t work properly. This can cause problems with bleeding or forming too many blood clots.


Pleural Disorders

Pleural disorders are conditions that affect the tissue that covers the outside of the lungs and lines the inside of the chest cavity.



Pneumonia is a lung infection that causes the air sacs to fill up with fluid or pus. This can make it hard to breathe.


Clinical Trials

The NHLBI leads and supports many clinical trials to help find new ways to prevent, detect, and treat heart, lung, blood, and sleep disorders

Fact Sheets and Handouts

The NHLBI develops materials for patients and health professionals on many heart, lung, blood, and sleep conditions. Information from the NHLBI is based on the latest scientific findings.