LAM Treatment


There is no cure for LAM, but there are effective medicines that can help relieve LAM symptoms and prevent complications. LAM is a progressive disease, meaning it gets worse over time. Oxygen therapy or a lung transplant may also be an option.


Your doctor may prescribe medicines to open up your airways and make it easier for you to breathe.

  • Sirolimus is a type of medicine called an mTOR inhibitor. Sirolimus may help control the abnormal growth and movement of LAM cells. The medicine may also help lung function, shrink kidney and lymph node growths, and reduce fluid in the lungs. Side effects can include diarrhea, nausea, acne, high blood cholesterol, swelling of your mouth and lips, and fluid buildup in your legs. Sirolimus may also affect your ovaries, liver, and kidneys and increase your risk of infections. Talk with your doctor about the benefits and risks of sirolimus, and whether it is an option for you.
  • Bronchodilators are medicines that can help relax the muscles around the airways if you are having trouble breathing or are wheezing.

Oxygen therapy

Your doctor may recommend oxygen therapy to increase the amount of oxygen your lungs receive and deliver to your blood. At first, you may need oxygen therapy only while exercising. It may also help to use it while sleeping. Eventually, you may need full-time oxygen therapy.

Learn more about oxygen therapy on our Lung Disease Treatments page. 

Lung transplant

Some patients who have severe lung damage due to advanced LAM may be eligible for a lung transplant.

Learn more about lung transplants on our Lung Disease Treatments page. 

Join a clinical trial

We lead or sponsor studies on LAM to find new treatments or better understand the disease. Find out if you or a loved one is eligible to join a clinical trial.

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