Blood Clotting Disorders Types

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Blood clotting disorders can either be inherited or acquired.

• “Inherited” means that your parents passed the gene for the disease on to you. Mutations, or changes in certain gene gene (jeen):
  The unit that passes heredity from parents to children. Genes are pieces of DNA and contain information for making a specific protein. , can make your blood more likely to form clots. Some genetic changes are more common than others. The common genetic changes are not as likely to cause serous blood clots as the rarer genetic changes. 
• “Acquired” means that you weren’t born with the disease, but you developed it due to another disease or condition.

Just because you have a blood clotting disorder does not mean that you will develop blood clots. But it does increase your chance of having blood clots throughout your lifetime.

Common inherited blood clotting disorders include:

• Factor V Leiden mutation, which occurs in 5% of people of European descent
• Prothrombin G20210A mutation (also called factor II mutation), which occurs in 2% of the population

Rare inherited blood clotting disorders include:

• Deficiencies in blood clotting proteins called protein C, protein S, and antithrombin
• Hyperhomocysteinemia
• Sticky platelet syndrome

Examples of acquired blood clotting disorders include:

• Antiphospholipid syndrome (APS): This is the most common acquired clotting disorder. APS is an autoimmune autoimmune (AW-toh-ih-MYOON):
  A term describing cells and antibodies that a person’s body makes to attack its own tissues, as happens in autoimmune diseases. condition where the body makes antibodies antibody (ANT-uh-baw-dee):
  A molecule that binds to a particular antigen, a substance that causes the body to have a particular immune response. Your immune system creates antibodies so that the particular antigen can be destroyed. that mistakenly attack cell molecules called phospholipids. Higher levels of APS antibodies in the blood raise the risk of blood clots.
• Disseminated intravascular coagulation (DIC): This condition is caused by an infection (such as Sepsis Sepsis (SEP-sis):
  A serious illness that results when the body has an overwhelming immune response to a bacterial infection. This response triggers the release of chemicals into the blood stream, which triggers inflammation to fight infection. The inflammation can damage organs and their systems. ) or an injury.