Sickle Cell Disease for Health Professionals

Clinical Practice Guidelines

The IOM (2011) defined clinical practice guidelines as "statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options."

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A physician talks to a young patient in a medical exam room.
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Research Feature
At St. Louis Children’s Hospital in Missouri, a 12-year-old boy waiting in an exam room held a tablet as he scrolled through a trivia game about sickle cell disease (SCD) – an inherited blood disorder that had brought him to the hospital for a regular visit. As he played the game, he won a badge each time he answered a question right. But happily, there were no wrong answers. That’s because the game’s goal is to explain – in simple terms – what many don’t know: that SCD affects more than 100,000 people in the U.S. and millions of others worldwide. That it is more common among Black children...

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