High Blood Cholesterol

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Clinical Practice Guidelines

The IOM (2011) defined clinical practice guidelines as "statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options."

Systematic Evidence Reviews

In 2011, the Institute of Medicine (IOM) defined a systematic evidence review as "a scientific investigation that focuses on a specific question and uses explicit, prespecified scientific methods to identify, select, assess, and summarize the findings of similar but separate studies.

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