Sickle Cell Disease report cover
Evidence-Based Management of Sickle Cell Disease: Expert Panel Report, 2014
Published Sep 2014
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These guidelines were developed by an expert panel composed of health care professionals with expertise in family medicine, general internal medicine, adult and pediatric hematology, psychiatry, transfusion medicine, obstetrics and gynecology, emergency department nursing, and evidence-based medicine. Panel members were selected by the NHLBI’s leadership.

The purpose of these guidelines is to help people living with sickle cell disease (SCD) receive appropriate care by providing the best science-based recommendations to guide practice decisions. The target audience is primary care providers and other clinicians, nurses, and staff who provide emergency or continuity care to individuals with SCD.

NHLBI sponsored the development of these guidelines to assist health care professionals in the management of common issues, including routine health maintenance, the recognition and treatment of common acute and chronic complications and comorbidities of SCD, as well as the indications for and monitoring of hydroxyurea and blood transfusion therapy. The guidelines address the care of infants, children, adolescents, and adults with SCD, with the goal of facilitating high-quality and appropriate care for all individuals with this disease.

These guidelines were developed by an expert panel composed of health care professionals with expertise in family medicine, general internal medicine, adult and pediatric hematology, psychiatry, transfusion medicine, obstetrics and gynecology, emergency department nursing, and evidence-based medicine. Panel members were selected by the NHLBI’s leadership.

The purpose of these guidelines is to help people living with sickle cell disease (SCD) receive appropriate care by providing the best science-based recommendations to guide practice decisions. The target audience is primary care providers and other clinicians, nurses, and staff who provide emergency or continuity care to individuals with SCD.

NHLBI sponsored the development of these guidelines to assist health care professionals in the management of common issues, including routine health maintenance, the recognition and treatment of common acute and chronic complications and comorbidities of SCD, as well as the indications for and monitoring of hydroxyurea and blood transfusion therapy. The guidelines address the care of infants, children, adolescents, and adults with SCD, with the goal of facilitating high-quality and appropriate care for all individuals with this disease.

Expert Panel Members

Co-Chairs

George Buchanan, M.D.
Professor of Pediatrics and Director
Division of Hematology-Oncology
Department of Pediatrics
University of Texas Southwestern Medical Center at Dallas

Barbara Yawn, M.D., M.S.P.H.
Director of Research
Olmsted Medical Center
Adjunct Professor, Family and Community Health
University of Minnesota

Members

Araba Afenyi-Annan, M.D., M.P.H. 
Assistant Professor 
University of North Carolina at Chapel Hill

Samir Ballas, M.D.
Professor, Department of Medicine
Thomas Jefferson University

Kathryn Hassell, M.D.
Professor of Medicine, Division of Hematology
Director, Colorado Sickle Cell Treatment and Research Center
University of Colorado Denver

Andra James, M.D., M.P.H.
Director, Women's Hemostasis and Thrombosis Clinic
Associate Professor of Obstetrics & Gynecology 
Associate Professor of Medicine
Duke University Medical Center

Lanetta Jordan, M.D., M.P.H., M.S.P.H.
Director of Sickle Cell Services 
Memorial Healthcare System
South Broward Hospital District

Sophie Lanzkron, M.D.
Director, Sickle Cell Center for Adults at Johns Hopkins

Richard Lottenberg, M.D.
Division of Hematology/Oncology
Professor of Medicine
University of Florida

William Savage, MD
Divisions of Transfusion Medicine and Pediatric Hematology
School of Medicine
Johns Hopkins University

Paula Tanabe, Ph.D., R.N., M.S.N., M.P.H.
Associate Professor
Duke University, Schools of Nursing and Medicine

Russell E. Ware, M.D., Ph.D.
Professor of Pediatrics and Vice-Chairman of Global Health
Director, Texas Children's Center for Global Health
Director, Baylor International Hematology Center of Excellence
Baylor College of Medicine and Texas Children's Hospital