3D rendering of normal and sickled cells

Sickle Cell Disease: Research, Programs, and Progress

Sickle cell disease affects about 100,000 Americans, many of whom are African American, and over 20 million people worldwide.

Publications and Resources

The NHLBI offers many sickle cell disease resources, including publications and videos, to help patients, their families, and health professionals. Explore these resources to learn more about important topics, such as tips for healthy living, treatments, and managing pain. Some publications are also available in Spanish.



Participate in a Clinical Trial

The NHLBI leads or sponsors many studies on sickle cell disease, advancing our knowledge and treatment of the condition—and you can help. Learn more about open and enrolling NHLBI clinical trials that are related to sickle cell disease and see if you or someone you know is eligible to participate in one of them.



Health Professionals

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Tools for Health Professionals

Find the latest report on sickle cell disease treatment and care, as well as patient education resources in English and Spanish, to help your patients learn more about the disease.

Get in Touch

Contact us with questions or to order resources on sickle cell disease from the NHLBI. You can also stay up to date on the latest news, events, and information from the NHLBI with our email alerts.
1-877-NHLBI4U (1-877-645-2448)

Open Monday through Friday, 8:30 a.m. to 5 p.m. Eastern time (closed on Federal holidays).

For access to free Telecommunications Relay Services (TRS), dial 7-1-1 on your telephone.

Postal Mail

NHLBI Center for Health Information
P.O. Box 30105
Bethesda, MD 20824-0105
United States