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Sickle Cell Disease: Research, Programs, and Progress

Sickle cell disease affects about 100,000 Americans, many of whom are African American, and over 20 million people worldwide.
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Find COVID-19 resources for sickle cell disease at the Centers for Disease Control and Prevention.

Concerned about COVID-19?

Read COVID-19 health alerts.
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COVID-19 and Sickle Cell Information for Clinicians

Find FAQs, registry information, and other resources at the American Society of Hematology.
Sickle Cell Branch Researchers

Conducting Sickle Cell Research at the NHLBI

Search published research and learn about ongoing research from our labs in the Sickle Cell Branch.
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Supporting Sickle Cell Research Across the Nation

Discover how our Division of Blood Diseases and Resources supports sickle cell disease research and clinical research centers nationwide.
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Funding Sickle Cell Disease Research and Care Around the World

Learn about the research we fund globally to improve treatment and care.
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Join an NHLBI Sickle Cell Clinical Trial

See if you or someone you love is eligible for an open and enrolling NHLBI clinical trial for sickle cell disease.
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Leading the Cure Sickle Cell Initiative

See how NHLBI-led collaborative research is paving the way for a cure for all patients who have sickle cell disease.
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Advancing Sickle Cell Treatments from Lab to Clinical Practice

Read about NHLBI’s Implementation Science and Genomics program and how it supports moving genomic findings into real-world settings.
Building on our legacy of excellence in sickle cell research

Explore Our Legacy of Excellence in Sickle Cell Research

Follow the timeline to read about our commitment to sickle cell disease research since 1948.

Publications and Resources

The NHLBI offers many sickle cell disease resources, including publications and videos, to help patients, their families, and health professionals. Explore these resources to learn more about important topics, such as tips for healthy living, treatments, and managing pain. Some publications are also available in Spanish.

Our Partners

The NHLBI recognizes the importance of partnering with communities and organizations that are invested in advancing research, education, and outreach to fully realize the dream of a generation free of sickle cell disease.
Learn more about Our Partners
Related Initiatives
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Blood Disorders and Blood Safety

The NHLBI is a global leader in blood-related research. Learn about NHLBI-supported research on blood disorders, including sickle cell disease, blood safety, transfusion medicine, and more.

Get in Touch

Contact us with questions or to order resources on sickle cell disease from the NHLBI. You can also stay up to date on the latest news, events, and information from the NHLBI with our email alerts.
Phone
1-877-NHLBI4U (1-877-645-2448)

Open Monday through Friday, 8:30 a.m. to 5 p.m. Eastern time (closed on Federal holidays).

For access to free Telecommunications Relay Services (TRS), dial 7-1-1 on your telephone.

Postal Mail

NHLBI Center for Health Information
P.O. Box 30105
Bethesda, MD 20824-0105
United States