Early Career

Provides support to current or recently completed NHLBI K01, K08, and K23 awardees to expand their current research objectives or to branch out to a study that resulted from the research conducted under the K award.

• Independent Clinical Trial Required (PA-18-372)
• No Independent Clinical Trials (PA-18-373) 

Prepares clinically trained individuals for careers that have a significant impact on the health-related research needs of the Nation. This program provides support and protected time for an intensive, supervised research career development experience in the fields of biomedical, behavioral, or clinical research, including translational research.

• Clinical Trial Required (PA-18-374)
• Independent Clinical Trials Not Allowed (PA-18-375)

Supports the career development of individuals with a clinical doctoral degree, who have the potential to develop into productive, clinical investigators, and who have made a commitment to focus their research endeavors on patient-oriented research.

• Clinical Trial Required (PA-18-395)
• No Independent Clinical Trials (PA-18-396)

The purpose of this award is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 supports productive professionals with quantitative (e.g., statistics, economics, computer science, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.

• Independent Clinical Trial Required (PA-18-363)
• Independent Clinical Trial Not Allowed (PA-18-369)

The NHLBI only uses the K01 for highly innovative research in humans only in the following areas:

• Epidemiological research that elucidates the mechanisms, etiology, pathogenesis, prevention, diagnosis and treatment of heart, lung, and blood diseases and sleep disorders.
• Biostatistics research leading to the development of innovative methods for designing studies and analyzing data in clinical and population-based research. This may include clinical trials and epidemiologic, genomic, proteomic, or metabolomic studies in heart, lung, blood diseases and sleep disorders.
• Outcomes research involving the comparison of screening, diagnostic, preventive or treatment strategies for heart, lung, blood diseases and sleep disorders.
• Implementation (T4 translation) research that addresses strategies for sustained adoption of proven, effective interventions in communities, health systems, clinicians, patients and families for heart, lung, and blood diseases and sleep disorders.
• State of the art research studies reflected above that use large data sources and electronic health records are encouraged.
   

• Clinical Trial Required (RFA-HL-19-025)
• Clinical Trial Not Allowed (RFA-HL-19-026)

Enhances the pool of highly trained investigators from diverse backgrounds underrepresented in research areas of interest to the NHLBI. Targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, and hematologic diseases and sleep disorders in the general and health disparities populations.

• Clinical Trial Required (PA-18-397)
• Independent Clinical Trial Not Allowed (PA-18-398)

Increases and maintains a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers or clinician-scientists from mentored research positions to independent, tenure-track or equivalent faculty positions, and to provide independent NIH research support during the transition that will help these individuals launch competitive, independent research careers. View the fact sheet for more information.

Provides administrative supplements to currently active NIH research grants to enhance the diversity of the research workforce.

Provides administrative supplements to currently active NIH research grants to support individuals with high potential to re-enter an active research career after a qualifying interruption for family or other responsibilities.