Various issues regarding use of stored tissue are covered in a November 7, 1997 issuance from OPRR (http://grants.nih.gov/grants/oprr/humansubjects/guidance/reposit.htm). Research Involving Human Biological Materials: Ethical Issues and Policy Guidance). A draft of a document being developed by the NIH (Research on Human Specimens) also covers these issues (http://www-cdp.ims.nci.nih.gov/policy.html). NCI has developed sample consent documents for repository activities (http://www.napbc.org/napbc/consent.htm and http://www.napbc.org/napbc/q&a.htm).
Discussions of additional issues can be found in the August, 1999 report from the National Bioethics Advisory Commission. Go to the National Bioethics Advisory Commission page, select Reports, and scroll down to Ethical Issues in Human Stem Cell Research, September 1999. (All these files are in Adobe PDF format.)
The following operating principles and NHLBI staff responsibilities are consistent with these documents, in particular the OPRR regulations.