The Digital Twins in Heart, Lung, Blood and Sleep Research Workshop took place virtually on September 25–26, 2025.

NIH supports the concept of Digital Twins as described in a 2024 report from the National Academies of Science, Engineering and Medicine (NASEM), as follows: "A Digital Twin is a set of virtual information constructs that mimics the structure, context, and behavior of a natural, engineered, or social system (or system-of-systems), is dynamically updated with data from its physical twin, has a predictive capability, and informs decisions that realize value. The bidirectional interaction between the virtual and the physical is central to the Digital Twin." This two-day virtual workshop will follow the NASEM report on Digital Twins framework while balancing Heart, Lung, Blood and Sleep (HLBS) research areas of interest.

The goals are to highlight the latest accomplishments in HLBS Digital Twins research and identify gaps and opportunities. This will help to continue building a community that brings clinicians, scientists, engineers, entrepreneurs, and program staff together and to accelerate NHLBI-specific Digital Twins research. The workshop will also highlight NHLBI data science resources such as the Biodata Catalyst and the NHLBI-AI that may support the development of Digital Twins.

Event Recording

Day 1: https://videocast.nih.gov/watch=56972
Day 2: https://videocast.nih.gov/watch=56973

Program Book

See the Program Book with full agenda and speakers biographies.

Contact Information:

For questions related to the workshop, please contact Dr. Julia Berzhanskaya at julia.berzhanskaya@nih.gov and Dr. Keyvan Farahani at farahank@mail.nih.gov.